Alveolar bone remodeling in orthodontic tooth movement (OTM) is a highly regulated
process that coordinates bone resorption by osteoclasts and new bone formation by …

Primary cilia, present on most mammalian cells, function as a sensor to sense the
environment change and transduce signaling. Loss of primary cilia causes a group of …

Intraflagellar transport (IFT) trains, the polymers composed of two multi-subunit complexes,
IFT-A and IFT-B, carry out bidirectional intracellular transport in cilia, vital for cilia biogenesis …

Intraflagellar transport proteins (IFT) are required for hedgehog (Hh) signalling transduction
that is essential for bone development, however, how IFT proteins regulate Hh signalling in …

Primary cilia are essential cellular organelles that are anchored at the cell surface
membrane to sense and transduce signaling. Intraflagellar transport (IFT) proteins are …

Primary cilia are highly conserved microtubule‐based organelles that project from the cell
surface into the extracellular environment and play important roles in mechanosensation …

Intraflagellar transport proteins (IFT) play important roles in cilia formation and organ
development. Partial loss of IFT80 function leads Jeune asphyxiating thoracic dystrophy …

20,230 protein-coding genes have been predicted from the analysis of the human genome
(neXtProt release 2018-01-17), and about 10% of them are still lacking functional …

Craniosynostosis (CS) is the second most prevalent inborn craniofacial malformation; it
results from the premature fusion of cranial sutures and leads to dimorphisms of variable …

Primary cilia and intraflagellar transport (IFT) proteins control a wide variety of processes
during tissue development and homeostasis. However, their role in regulation of stem cell …