Multifunctional nanomedicine with silica: Role of silica in nanoparticles for theranostic, imaging, and drug monitoring

F Chen, G Hableel, ER Zhao, JV Jokerst - Journal of colloid and interface …, 2018 - Elsevier
The idea of multifunctional nanomedicine that enters the human body to diagnose and treat
disease without major surgery is a long-standing dream of nanomaterials scientists …

Tailoring porous silicon for biomedical applications: from drug delivery to cancer immunotherapy

W Li, Z Liu, F Fontana, Y Ding, D Liu… - Advanced …, 2018 - Wiley Online Library
In the past two decades, porous silicon (PSi) has attracted increasing attention for its
potential biomedical applications. With its controllable geometry, tunable nanoporous …

Antibiotic-loaded nanoparticles targeted to the site of infection enhance antibacterial efficacy

S Hussain, J Joo, J Kang, B Kim, GB Braun… - Nature biomedical …, 2018 - nature.com
Bacterial resistance to antibiotics has made it necessary to resort to using antibacterial drugs
that have considerable toxicities. Here, we show that conjugation of vancomycin-loaded …

A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries

AP Mann, P Scodeller, S Hussain, J Joo… - Nature …, 2016 - nature.com
Traumatic brain injury (TBI) is a major health and socio-economic problem, but no
pharmacological agent is currently approved for the treatment of acute TBI. Thus, there is a …

Nonviral In Vivo Delivery of CRISPR-Cas9 Using Protein-Agnostic, High-Loading Porous Silicon and Polymer Nanoparticles

RB Fletcher, LD Stokes, IB Kelly III, KM Henderson… - ACS …, 2023 - ACS Publications
The complexity of CRISPR machinery is a challenge to its application for nonviral in vivo
therapeutic gene editing. Here, we demonstrate that proteins, regardless of size or charge …

Silicon-containing nanomedicine and biomaterials: materials chemistry, multi-dimensional design, and biomedical application

L Chen, S Zhang, Y Duan, X Song, M Chang… - Chemical Society …, 2024 - pubs.rsc.org
The invention of silica-based bioactive glass in the late 1960s has sparked significant
interest in exploring a wide range of silicon-containing biomaterials from the macroscale to …

Green synthesis of iron oxide nanoparticles mediated by filamentous fungi isolated from Sundarban mangrove ecosystem, India

S Mahanty, M Bakshi, S Ghosh, S Chatterjee… - BioNanoScience, 2019 - Springer
In the present study, biosynthesis of iron oxide nanoparticles (IONPs) was achieved using
three manglicolous fungi, STSP10 (Trichoderma asperellum), STSP 19 (Phialemoniopsis …

Advances in porous silicon–based nanomaterials for diagnostic and therapeutic applications

T Tieu, M Alba, R Elnathan… - Advanced …, 2019 - Wiley Online Library
This review provides a perspective on porous silicon (pSi)–based nanomaterials including
nanoparticles, nanowires, and thin films, that are currently being used in advanced therapy …

Synergistic approach towards the sustainable management of heavy metals in wastewater using mycosynthesized iron oxide nanoparticles: biofabrication, adsorptive …

S Mahanty, S Chatterjee, S Ghosh, P Tudu… - Journal of Water …, 2020 - Elsevier
In our study, novel mycosynthesis of ferromagnetic, monodispersed, spherical, crystalline
iron oxide nanoparticles (IO-NPs) of 73.05±15.47 nm were biofabricated using manglicolous …

[HTML][HTML] Self-sealing porous silicon-calcium silicate core-shell nanoparticles for targeted siRNA delivery to the injured brain

J Kang, J Joo, EE Kwon, M Skalak… - … (Deerfield Beach, Fla …, 2016 - ncbi.nlm.nih.gov
A single-step procedure to simultaneously load and protect high concentrations of siRNA in
porous silicon nanoparticles (pSiNPs) is presented. Treatment of pSiNPs with an aqueous …