Precision medicine aims to tailor medical treatment to match individual characteristics and to
stratify individuals to concentrate benefits and avoid harm. It has recently been joined by …

Background The use of proactive genetic screening for disease prevention and early
detection is not yet widespread. Professional practice guidelines from the American College …

Exome and genome sequencing are increasingly utilized in research studies and clinical
care and can provide clinically relevant information beyond the initial intent for sequencing …

Genomic screening at population scale generates many ethical considerations. One is the
normative role that people's preferences should play in determining access to genomic …

Purpose: Advances in clinical genomic sequencing capabilities, including reduced costs
and knowledge gains, have bolstered the consideration of genomic screening in healthy …

Delivering high quality genomics-informed care to patients requires accurate test results
whose clinical implications are understood. While other actors, including state agencies …

This paper demonstrates how greater engagement with liminality–as a concept and lived
experience–can expand scholarly conceptualisations of health/disease in contaminated …

Aim: Before population screening of 'healthy'individuals is widely adopted, it is important to
consider the harms and benefits of receiving positive results and how harms and benefits …

Population genetic screening (PGS) enables the detection of unselected individuals in the
general population who unknowingly carry a pathogenic variant in a gene that is causally …

Doubts have been raised about the value of DNA-based screening for low-prevalence
monogenic conditions following reports of testing this approach using available electronic …