Mechanisms of ephrin–Eph signalling in development, physiology and disease

A Kania, R Klein - Nature reviews Molecular cell biology, 2016 - nature.com
Eph receptor Tyr kinases and their membrane-tethered ligands, the ephrins, elicit short-
distance cell–cell signalling and thus regulate many developmental processes at the …

Proteoglycans and neuronal migration in the cerebral cortex during development and disease

N Maeda - Frontiers in neuroscience, 2015 - frontiersin.org
Chondroitin sulfate proteoglycans and heparan sulfate proteoglycans are major constituents
of the extracellular matrix and the cell surface in the brain. Proteoglycans bind with many …

The role of chondroitin sulfate proteoglycans in nervous system development

CP Mencio, RK Hussein, P Yu… - … of Histochemistry & …, 2021 - journals.sagepub.com
The orderly development of the nervous system is characterized by phases of cell
proliferation and differentiation, neural migration, axonal outgrowth and synapse formation …

[HTML][HTML] Impaired T3 uptake and action in MCT8-deficient cerebral organoids underlie Allan-Herndon-Dudley syndrome

F Salas-Lucia, S Escamilla, AC Bianco, A Dumitrescu… - JCI insight, 2024 - ncbi.nlm.nih.gov
Patients with mutations in the thyroid hormone (TH) cell transporter monocarboxylate
transporter 8 (MCT8) gene develop severe neuropsychomotor retardation known as Allan …

[HTML][HTML] Development of human retinal organoid models for bisphenol toxicity assessment

M Li, J Gong, L Ge, H Gao, J Yang, C Yang… - Ecotoxicology and …, 2022 - Elsevier
Abstract Bisphenols, including Bisphenol A (BPA), Tetrabromobisphenol A (TBBPA), and
Tetrabromobisphenol S (TBBPS), have been widely applied in the production of …

[HTML][HTML] Eph-ephrin signaling in nervous system development

KS Cramer, IJ Miko - F1000Research, 2016 - ncbi.nlm.nih.gov
Ephrins and Eph receptors enable contact-mediated interactions between cells at every
stage of nervous system development. In spite of their broad binding affinities, Eph proteins …

Crosstalk between intracellular and extracellular signals regulating interneuron production, migration and integration into the cortex

E Peyre, CG Silva, L Nguyen - Frontiers in cellular neuroscience, 2015 - frontiersin.org
During embryogenesis, cortical interneurons are generated by ventral progenitors located in
the ganglionic eminences of the telencephalon. They travel along multiple tangential paths …

Interneuron odyssey: molecular mechanisms of tangential migration

I Toudji, A Toumi, É Chamberland… - Frontiers in Neural …, 2023 - frontiersin.org
Cortical GABAergic interneurons are critical components of neural networks. They provide
local and long-range inhibition and help coordinate network activities involved in various …

EphrinA5 regulates cell motility by modulating Snhg15/DNA triplex-dependent targeting of DNMT1 to the Ncam1 promoter

CB Yildiz, T Kundu, J Gehrmann, J Koesling… - Epigenetics & …, 2023 - Springer
Cell–cell communication is mediated by membrane receptors and their ligands, such as the
Eph/ephrin system, orchestrating cell migration during development and in diverse cancer …

Overlapping migratory mechanisms between neural progenitor cells and brain tumor stem cells

N Zarco, E Norton, A Quiñones-Hinojosa… - Cellular and Molecular …, 2019 - Springer
Neural stem cells present in the subventricular zone (SVZ), the largest neurogenic niche of
the mammalian brain, are able to self-renew as well as generate neural progenitor cells …