The serendipitous story of sildenafil: an unexpected oral therapy for erectile dysfunction

I Goldstein, AL Burnett, RC Rosen… - Sexual medicine …, 2019 - academic.oup.com
Introduction The serendipitous discovery of sildenafil (Viagra [sildenafil citrate]) as a
treatment for erectile dysfunction (ED) is one of the most fascinating drug development …

Diagnosing sexual dysfunction in men and women: sexual history taking and the role of symptom scales and questionnaires

D Hatzichristou, PS Kirana, L Banner… - The journal of sexual …, 2016 - academic.oup.com
Introduction A detailed sexual history is the cornerstone for all sexual problem assessments
and sexual dysfunction diagnoses. Diagnostic evaluation is based on an in-depth sexual …

Platelet-rich plasma (PRP) improves erectile function: a double-blind, randomized, placebo-controlled clinical trial

E Poulios, I Mykoniatis, N Pyrgidis… - The journal of sexual …, 2021 - academic.oup.com
Background Animal studies postulate that platelet-rich plasma (PRP) injections improve key
elements of the pathophysiologic mechanisms leading to erectile dysfunction (ED). Aim To …

Quality of life and erectile dysfunction

SE Althof - Urology, 2002 - goldjournal.net
Quality of life (QOL) has become an important endpoint in the clinical research of sexual
dysfunction. This article reviews the QOL costs to men who have erectile dysfunction (ED) …

Strategies for managing sexual dysfunction induced by antidepressant medication

MJ Taylor, L Rudkin, P Bullemor‐Day… - Cochrane Database …, 2013 - cochranelibrary.com
Background Sexual dysfunction (including altered sexual desire, orgasmic and ejaculatory
dysfunction, erectile and other problems) is a relatively common side effect of antidepressant …

Phosphodiesterase 5 inhibitors for the treatment of erectile dysfunction: a trade-off network meta-analysis

L Chen, SEL Staubli, MP Schneider, AG Kessels, S Ivic… - European urology, 2015 - Elsevier
Context Erectile dysfunction (ED) is a major health care problem worldwide and
phosphodiesterase 5 inhibitors (PDE5Is) are the pharmacological treatment of choice …

[HTML][HTML] Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysis

B Gong, M Ma, W Xie, X Yang, Y Huang, T Sun… - … urology and nephrology, 2017 - Springer
Aims Erectile dysfunction (ED) is a major care problem worldwide. Tadalafil and sildenafil
are the two most common phosphodiesterase 5 inhibitors used to treat ED. This systematic …

Tadalafil in the treatment of erectile dysfunction following bilateral nerve sparing radical retropubic prostatectomy: a randomized, double-blind, placebo controlled trial

F Montorsi, HP Nathan, A Mccullough… - The Journal of …, 2004 - auajournals.org
Purpose: We evaluated the efficacy and safety of tadalafil 20 mg, taken on demand, in men
with erectile dysfunction following bilateral nerve sparing radical retropubic prostatectomy …

Erectile function outcome reporting after clinically localized prostate cancer treatment

AL Burnett, G Aus, ED Canby-Hagino, MS Cookson… - The Journal of …, 2007 - Elsevier
PURPOSE: In conjunction with the assignment to update the Guidelines for Management of
Clinically Localized Prostate Cancer, the American Urological Association Prostate Cancer …

Phosphodiesterase type 5 inhibitors for erectile dysfunction

CC Carson, TF Lue - BJU international, 2005 - Wiley Online Library
This is our first presentation of Great Drug Classes, and we start with a description of
phosphodiesterase type 5 inhibitors and their use in erectile dysfunction. This is an in‐depth …