Thalassemia in Pakistan

S Khaliq - Hemoglobin, 2022 - Taylor & Francis
The estimated population of Pakistan is approximately 225,633,392 (225 million). The
healthcare delivery system of Pakistan is complex because it includes healthcare …

Population screening for hemoglobinopathies

HW Goonasekera, CS Paththinige… - Annual review of …, 2018 - annualreviews.org
Hemoglobinopathies are the most common single-gene disorders in the world. Their
prevalence is predicted to increase in the future, and low-income hemoglobinopathy …

Epidemiology of Transfusion Transmitted Infection among Patients with β‐Thalassaemia Major in Pakistan

R Ahmed Kiani, M Anwar, U Waheed… - Journal of blood …, 2016 - Wiley Online Library
Introduction. Transfusion Transmitted Infections (TTIs) continue to be a major risk in
transfusions in many parts of the world. The transfusion‐dependent β‐thalassaemia patients …

Seroprevalence of hepatitis C, hepatitis B, cytomegalovirus, and human immunodeficiency viruses in multitransfused thalassemic children in upper Egypt

RA Mahmoud, AAM El-Mazary… - Advances in …, 2016 - Wiley Online Library
Background. Frequent blood transfusions in thalassemia major children expose them to the
risk of transfusion‐transmitted infections (TTIs). The aim of this study was to estimate the …

Beta thalassemia in 31,734 cases with HBB gene mutations: pathogenic and structural analysis of the common mutations; Iran as the crossroads of the Middle East

N Mahdieh, B Rabbani - Blood reviews, 2016 - Elsevier
Thalassemia is one of the most common single gene disorders worldwide. Nearly 80 to 90
million with minor beta thalassemia and 60–70 thousand affected infants are born annually …

[HTML][HTML] Novel genetic therapeutic approaches for modulating the severity of β‑thalassemia

F Amjad, T Fatima, T Fayyaz… - Biomedical …, 2020 - spandidos-publications.com
Thalassemia is a genetic haematological disorder that arises due to defects in the α and β‑
globin genes. Worldwide, 0.3‑0.4 million children are born with haemoglobinopathies per …

Prevalence of hepatitis C virus infection among thalassemia patients: a perspective from a multi-ethnic population of Pakistan

G Din, S Malik, I Ali, S Ahmed, JI Dasti - Asian Pacific journal of tropical …, 2014 - Elsevier
Objective To evaluate current situation regarding the prevalence of hepatitis C virus (HCV)
in thalassemic patients visiting a thalassemia centre in Rawalpindi District, Pakistan for …

Prevention programmes and prenatal diagnosis for beta thalassemia in Pakistan: A narrative review

M Ghafoor, MF Sabar, F Sabir - Journal of Pakistan Medical …, 2021 - go.gale.com
Beta Thalassemia is the most prevalent autosomal recessive genetic disorder that results
from errors in beta ([beta]) globin gene and ultimately reduced synthesis of [beta]-Globin …

Assessing parental knowledge about thalassemia in a thalassemia center of Karachi, Pakistan

H Maheen, F Malik, B Siddique, A Qidwai - Journal of genetic counseling, 2015 - Springer
Thalassemia is the leading haemoglobinopathy after sickle cell anemia that accounts for
1.5% of the global population. In Pakistan, every 1–4 per 1000 infants suffers from …

[HTML][HTML] Perceived stress and monetary burden among thalassemia patients and their caregivers

A Hisam, NA Tariq, H Irfan, B Arif… - Pakistan journal of …, 2018 - ncbi.nlm.nih.gov
Objective: To find the perceived stress level and monetary burden in the thalassemia
patients and their caregivers related to thalassemia treatment sessions. Methods: A …