Surgery is a mainstay treatment for patients with solid tumours. However, despite surgical
resection with a curative intent and numerous advances in the effectiveness of (neo) …

Surgery is an important treatment modality for the majority of solid organ cancers.
Unfortunately, cancer recurrence following surgery of curative intent is common, and …

Oncological surgery and anesthesia both stimulate the hypothalamic-pituitary-adrenal (HPA)
axis and the sympathetic nervous system (SNS). The HPA axis suppresses the host immune …

Oncological surgery and anesthesia both stimulate the hypothalamic-pituitary-adrenal (HPA)
axis and the sympathetic nervous system (SNS). The HPA axis suppresses the host immune …

In patients with cancer, opioids are principally used for the management of acute surgical
and chronic cancer‐related pain. However, opioids have many non‐analgesic effects …

IMMUNE PATHOGENESIS The principal line of defense against cancer cell invasion and
metastasis is established via the host's innate and adaptive immune response. The key …

Purpose Mortality among cancer patients is more commonly due to the effects of metastasis
and recurrence as opposed to the primary tumour. Various perioperative factors have been …

Metastasis can occur following surgical resection of solid tumors and metastasis is the main
cause of cancer death. The role of anesthetics used during surgery in cancer metastasis and …

Background Perioperative strategies can significantly influence long-term cancer outcomes.
Dexmedetomidine, an α 2-adrenoceptor agonist, is increasingly used perioperatively for its …

Addressing the hypothesis that anaesthetic-analgesic technique during cancer surgery
might influence recurrence or metastatic spread is a research priority. Propofol, which has …