Polygenic risk scores (PRSs) summarize the genetic predisposition of a complex human trait
or disease and may become a valuable tool for advancing precision medicine. However …

Single-cell genomic technologies are revealing the cellular composition, identities and
states in tissues at unprecedented resolution. They have now scaled to the point that it is …

The long delay before genomic technologies become available in low-and middle-income
countries is a concern from both scientific and ethical standpoints. Polygenic risk scores …

The ethics of the scientific study of Ancestors has long been debated by archaeologists,
bioanthropologists, and, more recently, ancient DNA (aDNA) researchers. This article …

The genotyping of millions of human samples has made it possible to evaluate variants
across the human genome for their possible association with risks for numerous diseases …

Equitable and just genetic research and clinical translation require an examination of the
ethical questions pertaining to vulnerable and marginalized communities. Autism research …

As the ancestral homeland of our species, Africa contains elevated levels of genetic diversity
and substantial population structure. Importantly, African genomes are heterogeneous: They …

Abstract The Human Cell Atlas (HCA) is a global partnership “to create comprehensive
reference maps of all human cells—the fundamental units of life–as a basis for both …

Population history-focused DNA and ancient DNA (aDNA) research in Africa has
dramatically increased in the past decade, enabling increasingly fine-scale investigations …

This report is the product of a major year-long initiative to acknowledge and reckon with past
injustice, as well as progress toward justice, within the American Society of Human Genetics …