Defining necrotizing enterocolitis: current difficulties and future opportunities

RM Patel, J Ferguson, SJ McElroy, M Khashu… - Pediatric …, 2020 - nature.com
Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality in hospitalized
infants. First classified through Bell staging in 1978, a number of additional definitions of …

Spontaneous intestinal perforation (SIP) will soon become the most common form of surgical bowel disease in the extremely low birth weight (ELBW) infant

JR Swanson, A Hair, RH Clark, PV Gordon - Journal of Perinatology, 2022 - nature.com
Recent data have revealed declines in the prevalence rates of NEC over the last decade in
premature infants. In contrast, SIP has either remained steady or risen during the same …

Association between year of birth and 1-year survival among extremely preterm infants in Sweden during 2004-2007 and 2014-2016

M Norman, B Hallberg, T Abrahamsson, LJ Björklund… - Jama, 2019 - jamanetwork.com
Importance Since 2004-2007, national guidelines and recommendations have been
developed for the management of extremely preterm births in Sweden. If and how more …

The Swedish neonatal quality register–contents, completeness and validity

M Norman, K Källén, E Wahlström… - Acta …, 2019 - Wiley Online Library
Abstract Aim To describe the Swedish Neonatal Quality Register (SNQ) and to determine its
completeness and agreement with other registers. Methods SNQ collects data for infants …

Probiotics for prevention of severe necrotizing enterocolitis: experience of New Zealand neonatal intensive care units

MP Meyer, SSW Chow, J Alsweiler, D Bourchier… - Frontiers in …, 2020 - frontiersin.org
Introduction: Necrotizing enterocolitis (NEC) affects mainly preterm infants, has a
multifactorial etiology and is associated with intestinal dysbiosis and disordered immunity …

Necrotizing enterocolitis: current understanding of the prevention and management

X Hu, H Liang, F Li, R Zhang, Y Zhu, X Zhu… - Pediatric Surgery …, 2024 - Springer
Necrotizing enterocolitis (NEC) is one of the diseases in neonates, with a high morbidity and
mortality rate, especially in preterm infants. This review aimed to briefly introduce the latest …

Neonatal morbidities and feeding tolerance outcomes in very preterm infants, before and after introduction of probiotic supplementation

A Mitha, SS Kruth, S Bjurman, A Rakow, S Johansson - Nutrients, 2022 - mdpi.com
While probiotics are reported to reduce the risks of neonatal morbidities, less is known about
probiotics and feeding tolerance. With this retrospective cohort study, we investigate whether …

Necrotising enterocolitis, late-onset sepsis and mortality after routine probiotic introduction in the UK

C Granger, E Dermyshi, E Roberts, LC Beck… - Archives of Disease in …, 2022 - fn.bmj.com
Objective To compare necrotising enterocolitis (NEC), late-onset sepsis (LOS), focal
intestinal perforation (FIP) and mortality in infants from a single neonatal unit before and …

Fecal amine metabolite analysis before onset of severe necrotizing enterocolitis in preterm infants: a prospective case–control study

N Deianova, S El Manouni El Hassani, EA Struijs… - Scientific reports, 2022 - nature.com
Infants developing necrotizing enterocolitis (NEC) have a different metabolomic profile
compared to controls. The potential of specific metabolomics, ie amino acids and amino …

Impact of delayed time to antibiotics in medical and surgical necrotizing enterocolitis

KE Chetta, KG Vincent, B Fanning, AB Klumb… - Children, 2023 - mdpi.com
This study investigated whether delayed receipt of antibiotics in infants with necrotizing
enterocolitis (NEC) is associated with disease severity. In this retrospective, single-center …