Redox modulation of stress resilience by Crocus sativus L. for potential neuroprotective and anti-neuroinflammatory applications in brain disorders: From molecular …

M Scuto, S Modafferi, F Rampulla, V Zimbone… - Mechanisms of Ageing …, 2022 - Elsevier
Recent evidence demonstrates that Crocus sativus L.(saffron) counteracts oxidative stress,
mitochondrial dysfunction and neuroinflammation, closely linked to initiation and …

Biochemical mechanisms of beneficial effects of beta-alanine supplements on cognition

GH Meftahi, GP Jahromi - Biochemistry (Moscow), 2023 - Springer
Using nutritional interventions to cure and manage psychiatric disorders is a promising tool.
In this regard, accumulating documents support strong relationships between the diet and …

Crocin, the main active saffron (Crocus sativus L.) constituent, as a potential candidate to prevent anxiety and depressive-like behaviors induced by unpredictable …

A Abbaszade-Cheragheali, F Beheshti, S Kakhki… - Neuroscience …, 2022 - Elsevier
Introduction Saffron, the dried stigmas of Crocus sativus L. is a famous and high-value
agricultural product of Iran exclusively used for cooking purpose and well known to treat …

Effects of swimming exercise combined with silymarin and vitamin C supplementation on hepatic inflammation, oxidative stress, and histopathology in elderly rats with …

F Aghaei, A Wong, M Zargani, A Sarshin, F Feizolahi… - Nutrition, 2023 - Elsevier
Objectives The aim of this study was to demonstrate that swimming exercise combined with
silymarin and vitamin C supplementation improves hepatic inflammation, oxidative stress …

Intranasal interferon-beta alleviates anxiety and depressive-like behaviors by modulating microglia polarization in an Alzheimer's disease model

M Farhangian, F Azarafrouz, S Chavoshinezhad… - Neuroscience …, 2023 - Elsevier
Alzheimer's disease (AD) patients frequently experience neuropsychiatric symptoms (NPS),
which are linked to a lower quality of life and a faster rate of disease progression. A growing …

Paradigms and Success Stories of Natural Products in Drug Discovery Against Neurodegenerative Disorders (NDDs)

S Singh, S Chib, MJ Akhtar, B Kumar… - Current …, 2024 - ingentaconnect.com
Neurodegenerative disorders (NDDs) are multifaceted complex disorders that have put a
great health and economic burden around the globe nowadays. The multi-factorial nature of …

New horizons for the study of saffron (Crocus sativus L.) and its active ingredients in the management of neurological and psychiatric disorders: A systematic review of …

S Han, Y Cao, X Wu, J Xu, Z Nie… - Phytotherapy Research, 2024 - Wiley Online Library
Saffron (Crocus sativus), as an herbal medicine, has been extensively investigated for
treating neurological and psychiatric disorders. This systematic review aimed to assess the …

Date palm spathe extract reverses chronic stress‐induced changes in dendritic arborization in the amygdala and impairment of hippocampal long‐term potentiation

M Hadipour, GH Meftahi, GP Jahromi - Synapse, 2023 - Wiley Online Library
Chronic restraint stress induces anxiety‐like behaviors and emotional abnormalities via an
alteration of synaptic remodeling in the amygdala and the hippocampus. Given that the date …

Comparative effects of the alcoholic extract of Terminalia chebula and crocin on stress‑induced anxiety‑like behavior and memory impairment in male rats

GP Jahromi, Z Jangravi, M Hadipour, H Shirvani… - Acta Neurobiologiae …, 2023 - ane.pl
Crocin and Terminalia chebula (T. chebula) were proven to have neuroprotective effects. In
this study, we evaluated the preventive effects of crocin and alcoholic extract of the T …

Laterality dissociation of ventral hippocampus inhibition in learning and memory, glial activation and neural arborization in response to chronic stress in male Wistar …

MS Brojeni, M Korani, GH Meftahi, N Davoodian… - Journal of Chemical …, 2022 - Elsevier
Many studies suggest that animals exhibit lateralized behaviors during stressful situations.
However, which brain structure in each hemisphere underlies such lateralized function is …