Infection-associated thymic atrophy

M Luo, L Xu, Z Qian, X Sun - Frontiers in immunology, 2021 - frontiersin.org
The thymus is a vital organ of the immune system that plays an essential role in thymocyte
development and maturation. Thymic atrophy occurs with age (physiological thymic atrophy) …

Thymus, undernutrition, and infection: approaching cellular and molecular interactions

W Savino, J Durães, C Maldonado-Galdeano… - Frontiers in …, 2022 - frontiersin.org
Undernutrition remains a major issue in global health. Low protein-energy consumption,
results in stunting, wasting and/or underweight, three deleterious forms of malnutrition that …

Protoplast Isolation and Shoot Regeneration from Protoplast-Derived Callus of Petunia hybrida Cv. Mirage Rose

HH Kang, AH Naing, CK Kim - Biology, 2020 - mdpi.com
Despite the increasing use of protoplasts in plant biotechnology research, shoot
regeneration from protoplasts remains challenging. In this study, we investigated the factors …

Drugs and nanoformulations for the management of Leishmania infection: a patent and literature review (2015-2022)

M Verdan, I Taveira, F Lima, F Abreu… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Leishmaniasis is an important disease caused by parasites of the Leishmania.
Due to the urgent need for financial incentives and research and development of new anti …

A fingerprint of plasma proteome alteration after local tissue damage induced by Bothrops leucurus snake venom in mice

J dos Santos Cavalcante, CAS de Almeida… - Journal of …, 2022 - Elsevier
Bothrops spp. is responsible for about 70% of snakebites in Brazil, causing a diverse and
complex pathophysiological condition. Bothrops leucurus is the main species of medical …

The thymus road to a T cell: migration, selection, and atrophy

M Ruiz Pérez, P Vandenabeele… - Frontiers in …, 2024 - frontiersin.org
The thymus plays a pivotal role in generating a highly-diverse repertoire of T lymphocytes
while preventing autoimmunity. Thymus seeding progenitors (TSPs) are a heterogeneous …

Leishmania infection upregulates and engages host macrophage Argonaute 1, and system-wide proteomics reveals Argonaute 1-dependent host response

A Moradimotlagh, S Chen, S Koohbor… - Frontiers in …, 2023 - frontiersin.org
Leishmania donovani, an intracellular protozoan parasite, is the causative agent of visceral
leishmaniasis, the most severe form of leishmaniasis in humans. It is becoming increasingly …

Bioluminescent Imaging Identifies Thymus, As Overlooked Colonized Organ, in a Chronic Model of Leishmania donovani Mouse Visceral Leishmaniasis

B Dominguez-Asenjo, C Gutierrez-Corbo… - ACS Infectious …, 2021 - ACS Publications
The search for new drugs against neglected parasitic diseases has experienced a major
boost in recent years with the incorporation of bioimaging techniques. Visceral …

Validation of a feed protocol in a mouse model that mimics marasmic malnutrition

T Ferreira-Paes, P Seixas-Costa… - Frontiers in Veterinary …, 2021 - frontiersin.org
Host nutritional status directly interferes with immunity and/or susceptibility to infectious
diseases. To understand the mechanisms behind this relationship, the use of animal models …

The Teleost Thymus in Health and Disease: New Insights from Transcriptomic and Histopathological Analyses of Turbot, Scophthalmus maximus

P Ronza, D Robledo, AP Losada, R Bermúdez… - Biology, 2020 - mdpi.com
The thymus is a primary lymphoid organ that plays a pivotal role in the adaptive immune
system. The immunobiology of the thymus in fish is considered to be similar to that of …