Simple Summary Hypoxia is defined as the inadequate supply of oxygen in tissues. Regions of acute and chronic hypoxia are a universal feature of the tumor microenvironment and a …
Z Zhou, Y Dang, M Zhou, L Li, C Yu… - Proceedings of the …, 2016 - National Acad Sciences
Codon usage biases are found in all eukaryotic and prokaryotic genomes, and preferred codons are more frequently used in highly expressed genes. The effects of codon usage on …
F Zhao, Z Zhou, Y Dang, H Na… - Proceedings of the …, 2021 - National Acad Sciences
Codon usage bias is a fundamental feature of all genomes and plays an important role in determining gene expression levels. The codon usage was thought to influence gene …
J Fu, Y Dang, C Counter, Y Liu - Journal of Biological Chemistry, 2018 - ASBMB
KRAS and HRAS are highly homologous oncogenic Ras GTPase family members that are mutated in a wide spectrum of human cancers. Despite having high amino acid identity …
Z Zhou, Y Dang, M Zhou, H Yuan, Y Liu - Elife, 2018 - elifesciences.org
Codon usage biases are found in all genomes and influence protein expression levels. The codon usage effect on protein expression was thought to be mainly due to its impact on …
Precise regulation of transcription by RNA polymerase II (RNAPII) is critical for organismal growth and development. However, what determines whether an engaged RNAPII will …
Y Lee, SH Dho, J Lee, JH Hwang, M Kim… - … & molecular medicine, 2022 - nature.com
Despite numerous observations regarding the relationship between DNA methylation changes and cancer progression, only a few genes have been verified as diagnostic …
JA Williams - Current gene therapy, 2014 - ingentaconnect.com
DNA vaccines are a rapidly deployed next generation vaccination platform for treatment of human and animal disease. DNA delivery devices, such as electroporation and needle free …
C Molteni, D Forni, R Cagliani… - Journal of General …, 2023 - microbiologyresearch.org
Poxviruses (family Poxviridae) have long dsDNA genomes and infect a wide range of hosts, including insects, birds, reptiles and mammals. These viruses have substantial incidence …