[HTML][HTML] Fight fire with fire: Neurobiology of capsaicin-induced analgesia for chronic pain
Capsaicin, the pungent ingredient in chili peppers, produces intense burning pain in
humans. Capsaicin selectively activates the transient receptor potential vanilloid 1 (TRPV1) …
humans. Capsaicin selectively activates the transient receptor potential vanilloid 1 (TRPV1) …
[HTML][HTML] Topical treatments for localized neuropathic pain
R Casale, Z Symeonidou, M Bartolo - Current pain and headache reports, 2017 - Springer
Abstract Purpose of Review Topical therapeutic approaches in localized neuropathic pain
(LNP) syndromes are increasingly used by both specialists and general practitioners, with a …
(LNP) syndromes are increasingly used by both specialists and general practitioners, with a …
TRP channels in COVID-19 disease: potential targets for prevention and treatment
Abstract Coronavirus disease 2019 [COVID-19] is a global health threat caused by severe
acute respiratory syndrome coronavirus 2 [SARS-CoV2] that requires two proteins for entry …
acute respiratory syndrome coronavirus 2 [SARS-CoV2] that requires two proteins for entry …
The role of adenosine receptor ligands on inflammatory pain: Possible modulation of TRPV1 receptor function
Chronic pain has a debilitating consequences on health and lifestyle. The currently
available analgesics are often ineffective and accompanied by undesirable adverse effects …
available analgesics are often ineffective and accompanied by undesirable adverse effects …
Cisplatin provokes peripheral nociception and neuronal features of therapy-induced senescence and calcium dysregulation in rats
Abstract Therapy-Induced Senescence (TIS) is a form of senescence that is typically
described in malignant cells in response to the exposure of cancer chemotherapy or …
described in malignant cells in response to the exposure of cancer chemotherapy or …
Cross‐linked enzyme aggregates of recombinant Candida antarctica lipase B for the efficient synthesis of olvanil, a nonpungent capsaicin analogue
T Diaz‐Vidal, VP Armenta‐Perez… - Biotechnology …, 2019 - Wiley Online Library
Despite the proven therapeutic role of capsaicin in human health, its usage is still hampered
by its high pungency. In this sense, nonpungent capsaicin analogues as olvanil are a …
by its high pungency. In this sense, nonpungent capsaicin analogues as olvanil are a …
[HTML][HTML] Oral somatosensory alterations and salivary dysfunction in head and neck cancer patients
RR Riantiningtyas, A Valenti, A Dougkas… - Supportive Care in …, 2023 - Springer
Purpose Patients with head and neck cancer (HNC) are at high risk of malnutrition due to
eating difficulties partly mediated by sensory alterations and salivary dysfunction. Clinical …
eating difficulties partly mediated by sensory alterations and salivary dysfunction. Clinical …
Interaction of the synthetic cannabinoid WIN55212 with tramadol on nociceptive thresholds and core body temperature in a chemotherapy-induced peripheral …
Chemotherapy-induced peripheral neuropathy (CIPN) is a significant adverse effect of many
anticancer drugs. Current strategies for the management of CIPN pain are still largely unmet …
anticancer drugs. Current strategies for the management of CIPN pain are still largely unmet …
Topical drug therapeutics for neuropathic pain
TJ Coderre - Expert Opinion on Pharmacotherapy, 2018 - Taylor & Francis
Introduction: Neuropathic pain (NP) is a particularly severe and intractable chronic condition
that is not well treated by commonly recommended systemic pharmacological therapies …
that is not well treated by commonly recommended systemic pharmacological therapies …
Novel TRPV1 modulators with reduced pungency induce analgesic effects in mice
A Treat, V Henri, J Liu, J Shen, M Gil-Silva… - ACS …, 2022 - ACS Publications
Capsaicin, the compound in hot chili peppers responsible for their pungency and an agonist
of the transient receptor potential cation channel, subfamily V, member 1 (TRPV1), has long …
of the transient receptor potential cation channel, subfamily V, member 1 (TRPV1), has long …