Alzheimer's disease (AD) is the most common type of dementia and a neurodegenerative
disorder characterized by memory deficits especially forgetting recent information, recall …

Convection-enhanced delivery (CED) is a method used to increase transport of therapeutics
in and around brain tumors. CED works through locally applying a pressure differential to …

Arterial spin labeling (ASL) has undergone significant development since its inception, with
a focus on improving standardization and reproducibility of its acquisition and quantification …

The brain exhibits substantial diurnal variation in physiology and function, but neuroscience
studies rarely report or consider the effects of time of day. Here, we examined variation in …

Neuroplasticity refers to the brain's ability to undergo structural and functional adaptations in
response to experience, and this process is associated with learning, memory and …

Current theories suggest that waste solutes are cleared from the brain via cerebrospinal fluid
(CSF) flow, driven by pressure pulsations of possibly both cardiac and respiratory origin. In …

Venous system pathologies have increasingly been linked to clinically relevant disorders of
CSF circulation whereas the exact coupling mechanisms still remain unknown. In this work …

Meningeal lymphatic vessels (mLVs), the functional lymphatic system present in the
meninges, are the key drainage route responsible for the clearance of molecules, immune …

Arterial spin labeling (ASL) is a powerful noncontrast magnetic resonance imaging (MRI)
technique that enables quantitative evaluation of brain perfusion. To optimize the clinical …

Migraine is a symptomatically heterogeneous condition, of which headache is just one
manifestation. Migraine is a disorder of altered sensory thresholding, with hypersensitivity …