The effect of insomnia on development of Alzheimer's disease

S Sadeghmousavi, M Eskian, F Rahmani… - Journal of …, 2020 - Springer
Alzheimer's disease (AD) is the most common type of dementia and a neurodegenerative
disorder characterized by memory deficits especially forgetting recent information, recall …

Convection-enhanced delivery: connection to and impact of interstitial fluid flow

CA Stine, JM Munson - Frontiers in oncology, 2019 - frontiersin.org
Convection-enhanced delivery (CED) is a method used to increase transport of therapeutics
in and around brain tumors. CED works through locally applying a pressure differential to …

[HTML][HTML] ExploreASL: an image processing pipeline for multi-center ASL perfusion MRI studies

HJMM Mutsaerts, J Petr, P Groot, P Vandemaele… - Neuroimage, 2020 - Elsevier
Arterial spin labeling (ASL) has undergone significant development since its inception, with
a focus on improving standardization and reproducibility of its acquisition and quantification …

Time of day is associated with paradoxical reductions in global signal fluctuation and functional connectivity

C Orban, R Kong, J Li, MWL Chee, BTT Yeo - PLoS biology, 2020 - journals.plos.org
The brain exhibits substantial diurnal variation in physiology and function, but neuroscience
studies rarely report or consider the effects of time of day. Here, we examined variation in …

[HTML][HTML] The combined influences of exercise, diet and sleep on neuroplasticity

JW Pickersgill, CV Turco, K Ramdeo, RS Rehsi… - Frontiers in …, 2022 - frontiersin.org
Neuroplasticity refers to the brain's ability to undergo structural and functional adaptations in
response to experience, and this process is associated with learning, memory and …

Respiratory influence on cerebrospinal fluid flow–a computational study based on long-term intracranial pressure measurements

V Vinje, G Ringstad, EK Lindstrøm, LM Valnes… - Scientific reports, 2019 - nature.com
Current theories suggest that waste solutes are cleared from the brain via cerebrospinal fluid
(CSF) flow, driven by pressure pulsations of possibly both cardiac and respiratory origin. In …

Deep breathing couples CSF and venous flow dynamics

JM Kollmeier, L Gürbüz-Reiss, P Sahoo, S Badura… - Scientific reports, 2022 - nature.com
Venous system pathologies have increasingly been linked to clinically relevant disorders of
CSF circulation whereas the exact coupling mechanisms still remain unknown. In this work …

Emerging roles of meningeal lymphatic vessels in Alzheimer's disease

X Guo, G Zhang, Q Peng, L Huang… - Journal of …, 2023 - content.iospress.com
Meningeal lymphatic vessels (mLVs), the functional lymphatic system present in the
meninges, are the key drainage route responsible for the clearance of molecules, immune …

Arterial spin labeling applications in pediatric and adult neurologic disorders

S Bambach, M Smith, PP Morris… - Journal of Magnetic …, 2022 - Wiley Online Library
Arterial spin labeling (ASL) is a powerful noncontrast magnetic resonance imaging (MRI)
technique that enables quantitative evaluation of brain perfusion. To optimize the clinical …

Migraine is more than just headache: is the link to chronic fatigue and mood disorders simply due to shared biological systems?

N Karsan, PJ Goadsby - Frontiers in Human Neuroscience, 2021 - frontiersin.org
Migraine is a symptomatically heterogeneous condition, of which headache is just one
manifestation. Migraine is a disorder of altered sensory thresholding, with hypersensitivity …