Lipids are crucial components of cellular function owing to their role in membrane formation,
intercellular signaling, energy storage, and homeostasis maintenance. In the brain, lipid …

High-density lipoproteins (HDL) play a key role in cholesterol homeostasis maintenance in
the central nervous system (CNS), by carrying newly synthesized cholesterol from astrocytes …

Identifying reproducible and interpretable biomarkers for Alzheimer's disease (AD) detection
remains a challenge. AD detection using multi-center datasets can expand the sample size …

Alzheimer's disease (AD) is increasingly recognized as being intertwined with the
dysregulation of lipid metabolism. Lipids are a significant class of nutrients vital to all …

Abstract Phospholipid Transfer Protein (PLTP) transfers amphiphilic lipids between
circulating lipoproteins and between lipoproteins, cells and tissues. Indeed, PLTP is a major …

Parkinson's disease (PD) is the second most common neurodegenerative disease, and its
prevalence is increasing. Currently, no effective therapies for PD exist. Marine-derived …

The immediate early gene Arc is a master regulator of synaptic function and a critical
determinant of memory consolidation. Here, we show that Arc interacts with dynamic …

Alzheimer's disease (AD) is the most common cause of dementia. A genome‐wide
association study has shown that several AD risk genes are involved in lipid metabolism …

Atherosclerosis was considered to induce many vascular-related complications, such as
acute myocardial infarction and stroke. Abnormal lipid metabolism and its peroxidation …

Clinical depression is one of the most common and debilitating psychiatric disorders and
contributes to increased risks of disability and suicide. Differentially expressed serum …