Systemic immunomodulatory treatments for atopic dermatitis: living systematic review and network meta-analysis update

AM Drucker, M Lam, D Prieto-Merino, R Malek… - JAMA …, 2024 - jamanetwork.com
Importance There are multiple approved systemic treatments for atopic dermatitis.
Lebrikizumab is a newly licensed biologic medication that has been compared to placebo in …

A systematic review investigating the proportion of clinical images shared in prospective randomized controlled trials involving patients with atopic dermatitis and …

S Polesie, M Alsterholm - Journal of Dermatological Treatment, 2024 - Taylor & Francis
Purpose: For individuals with atopic dermatitis (AD), interpreting scientific papers that
present clinical outcomes including the Eczema Area and Severity Index (EASI) and …

The levels of amino acid metabolites in serum induce the pathogenesis of atopic dermatitis by mediating the inflammatory protein S100A12

Y Zhang, H Xu, Y Tang, Y Li, F Zheng - Scientific Reports, 2024 - nature.com
Atopic dermatitis (AD) is a chronic inflammatory skin disease affecting tens of millions of
people globally. The causal relationship between metabolites and AD pathology has not yet …

International consensus on methotrexate dosing for patients with atopic dermatitis: An eDelphi study

AGM Caron, AM van Huizen… - Journal of the …, 2025 - Wiley Online Library
Background Despite the widespread off‐label use of methotrexate (MTX) for the treatment of
atopic dermatitis (AD), there is limited high‐quality evidence on dosing regimens and …

[HTML][HTML] Consensus on the therapeutic management of atopic dermatitis‒Brazilian Society of Dermatology: an update on phototherapy and systemic therapy using e …

RL Orfali, D Lorenzini, A Bressan… - Anais brasileiros de …, 2023 - SciELO Brasil
This publication is an update of the “Consensus on the therapeutic management of atopic
dermatitis-Brazilian Society of Dermatology” published in 2019, considering the novel …

A prospective observational cohort study comparing the treatment effectiveness and safety of ciclosporin, dupilumab and methotrexate in adult and paediatric patients …

H Alexander, R Malek, D Prieto-Merino… - British Journal of …, 2024 - academic.oup.com
Background The main conventional systemic treatments for atopic dermatitis (AD) are
methotrexate (MTX) and ciclosporin (CyA). Dupilumab was the first novel systemic agent to …

Drug Survival of Dupilumab, Methotrexate, and Cyclosporine A in Children With Atopic Dermatitis

LP van der Rijst, E Kamphuis, MLA Schuttelaar… - JAMA …, 2025 - jamanetwork.com
Importance Dupilumab, methotrexate (MTX), and cyclosporine A (CsA) are valuable
treatment options for pediatric patients with refractory moderate to severe atopic dermatitis …

[HTML][HTML] Atopic Dermatitis-Related Problems in Daily Life, Goals of Therapy and Deciding Factors for Systemic Therapy: A Review

L Lugović-Mihić, E Barac, R Tomašević, E Parać… - Pharmaceuticals, 2024 - mdpi.com
Background/Objectives/Methods: Atopic dermatitis (AD) impacts various aspects of patients'
lives including personal life, psychological aspects/disturbances (eg, depression, anxiety, or …

How can we optimize the use of methotrexate to treat pediatric patients with inflammatory skin diseases?

K Kiełbowski, E Bakinowska… - Expert Opinion on Drug …, 2024 - Taylor & Francis
Introduction Methotrexate (MTX) is a folic acid antagonist used in clinical practice in
oncology and rheumatology, as well as in the treatment of inflammatory skin conditions in …

The effects of ciclosporin and methotrexate on kidney function in the treatment of severe atopic dermatitis in children: results from the TREAT trial

G Bruce, A Rosala-Hallas, AP Jones… - British Journal of …, 2024 - academic.oup.com
Ciclosporin (CyA) and methotrexate (MTX) are frequently prescribed drugs for the treatment
of atopic dermatitis in children and young people. Both can affect renal function and frequent …