In times of coronavirus disease 2019 (COVID-19), the impact of severe acute respiratory
syndrome (SARS)-coronavirus (CoV)-2 infection on pregnancy is still unclear. The presence …

To cite this article: Maurer M, Bader M, Bas M, Bossi F, Cicardi M, Cugno M, Howarth P,
Kaplan A, Kojda G, Leeb‐Lundberg F, Lötvall J, Magerl M. New topics in bradykinin …

Introduction: Kinins are peptide mediators exerting their pro-inflammatory actions by the
selective stimulation of two distinct G-protein coupled receptors, termed BKB1R and BKB2R …

An important role for liver in the regulation of adipose tissue thermogenesis upon cold
exposure has been suggested; however, the underlying mechanisms remain incompletely …

Introduction Obesity-related metabolic diseases occur as a result of disruptions in white
adipose tissue (WAT) plasticity, especially through visceral fat accumulation and adipocyte …

Endogenous kinins are important vasoactive peptides whose effects are mediated by two G-
Protein-coupled receptors (R), named B2R (constitutive) and B1R (inducible). They are …

Plasma kallikrein (PK) is a serine protease generated from plasma prekallikrein, an
abundant circulating zymogen expressed by the Klkb1 gene. The physiological actions of …

Background Kinin B1 receptor (B1R) is induced by the oxidative stress in models of diabetes
mellitus. This study aims at determining whether B1R activation could perpetuate the …

The kinin B1 receptor plays an important role in mediating the inflammatory effects of the
kallikrein–kinin pathway. The recent development of orally available non-peptidic …

Brown adipose tissue (BAT) is known to secrete regulatory factors in response to
thermogenic stimuli. Components of the BAT secretome may exert local effects that …