Concepts of myelin and myelination in neuroradiology

AJ Barkovich - American Journal of Neuroradiology, 2000 - Am Soc Neuroradiology
Until the advent of MR imaging, knowledge of the structure of myelin and the process of
myelination were of little importance to the neuroradiologist. Other than some mild changes …

The role of magnetic resonance techniques in understanding and managing multiple sclerosis.

DH Miller, RI Grossman, SC Reingold… - Brain: a journal of …, 1998 - academic.oup.com
Magnetic resonance (MR) techniques have had a major impact in the last 10-15 years in
understanding and managing multiple sclerosis. This review summarizes the current uses of …

Quantitative pathological evidence for axonal loss in normal appearing white matter in multiple sclerosis

N Evangelou, MM Esiri, S Smith… - Annals of Neurology …, 2000 - Wiley Online Library
We assessed axonal loss in the normal appearing white matter of the corpus callosum in
postmortem brains of patients with multiple sclerosis, using quantitative measures of both …

Magnetization transfer changes in the normal appering white matter precede the appearance of enhancing lesions in patients with multiple sclerosis

M Filippi, MA Rocca, G Martino… - Annals of …, 1998 - Wiley Online Library
Serial monthly magenetization transfer (MT) imaging was performed to evaluate whether a
change of the normal appearing white matter (NAWM), which precedes the appearance of …

Brain and spinal cord abnormalities in multiple sclerosis. Correlation between MRI parameters, clinical subtypes and symptoms.

GJ Nijeholt, MA Van Walderveen… - Brain: a journal of …, 1998 - academic.oup.com
We investigated various magnetic resonance MRI parameters for both brain and spinal cord
to see if any improved the clinicoradiological correlation in multiple sclerosis. Ninety-one …

Microvascular abnormality in relapsing-remitting multiple sclerosis: perfusion MR imaging findings in normal-appearing white matter

M Law, AM Saindane, Y Ge, JS Babb, G Johnson… - Radiology, 2004 - pubs.rsna.org
PURPOSE: To prospectively determine hemodynamic changes in the normal-appearing
white matter (NAWM) of patients with relapsing-remitting multiple sclerosis (RR-MS) by …

Multiple sclerosis: the role of MR imaging

Y Ge - American Journal of Neuroradiology, 2006 - Am Soc Neuroradiology
MR offers by far the most sensitive technique for detecting multiple sclerosis (MS) lesions
and has proved to be an important paraclinical tool for diagnosing MS and monitoring …

Is the magnetization transfer ratio a marker for myelin in multiple sclerosis?

IM Vavasour, C Laule, DKB Li… - Journal of Magnetic …, 2011 - Wiley Online Library
Purpose To investigate the correlation between water content (WC) and magnetization
transfer ratio (MTR) in normal and multiple sclerosis (MS) brain. The MTR has been …

Mean diffusivity and fractional anisotropy histograms of patients with multiple sclerosis

M Cercignani, M Inglese, E Pagani… - American journal of …, 2001 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Compared with conventional T2-weighted MR imaging,
diffusion tensor MR imaging provides quantitative indices with increased specificity to the …

Magnetisation transfer ratio and mean diffusivity of normal appearing white and grey matter from patients with multiple sclerosis

M Cercignani, M Bozzali, G Iannucci, G Comi… - Journal of Neurology …, 2001 - jnnp.bmj.com
OBJECTIVE To assess the feasibility of a new technique based on diffusion anisotropy to
segment white and grey matter of the brain. To use this technique to measure the mean …