Simple Summary Glioma is one of the most common primary central nervous system (CNS)
tumors, and its molecular diagnosis is crucial. However, surgical resection or biopsy is risky …

H3. 3 is a highly conserved nonreplicative histone variant. H3. 3 is enriched in promoters
and enhancers of active genes, but it is also found within suppressed heterochromatin …

Paediatric high-grade gliomas are among the most common malignancies found in children.
Despite morphological similarities to their adult counterparts, there are profound biological …

The 2021 edition of the World Health Organization (WHO) classification of central nervous
system tumors introduces significant revisions across various tumor types. These updates …

Abstract Knowledge of the molecular pathways of pediatric high-grade gliomas is
increasing. Gliomas with mismatch repair deficiency do not currently comprise a distinct …