Chemical strategies to engineer hydrogels for cell culture

J Lou, DJ Mooney - Nature Reviews Chemistry, 2022 - nature.com
Two-dimensional and three-dimensional cell culture systems are widely used for biological
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …

Structurally dynamic hydrogels for biomedical applications: pursuing a fine balance between macroscopic stability and microscopic dynamics

K Zhang, Q Feng, Z Fang, L Gu, L Bian - Chemical Reviews, 2021 - ACS Publications
Owing to their unique chemical and physical properties, hydrogels are attracting increasing
attention in both basic and translational biomedical studies. Although the classical hydrogels …

Hydrogel bioink reinforcement for additive manufacturing: a focused review of emerging strategies

D Chimene, R Kaunas, AK Gaharwar - Advanced materials, 2020 - Wiley Online Library
Bioprinting is an emerging approach for fabricating cell‐laden 3D scaffolds via robotic
deposition of cells and biomaterials into custom shapes and patterns to replicate complex …

3D bioprinting of cell‐laden hydrogels for improved biological functionality

SM Hull, LG Brunel, SC Heilshorn - Advanced Materials, 2022 - Wiley Online Library
The encapsulation of cells within gel‐phase materials to form bioinks offers distinct
advantages for next‐generation 3D bioprinting. 3D bioprinting has emerged as a promising …

Cyclodextrin polymers: Structure, synthesis, and use as drug carriers

Z Liu, L Ye, J Xi, J Wang, Z Feng - Progress in Polymer Science, 2021 - Elsevier
Cyclodextrin-based polymers (CDPs) are amphiphilic macromolecules owing to their unique
structure and the presence of multiple hydroxyl groups. These polymers have become …

Tailoring gelation mechanisms for advanced hydrogel applications

V Nele, JP Wojciechowski… - Advanced Functional …, 2020 - Wiley Online Library
Hydrogels are one of the most commonly explored classes of biomaterials. Their chemical
and structural versatility has enabled their use across a wide range of applications, including …

Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G Jin… - Chemical …, 2017 - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Mechanics of 3D cell–hydrogel interactions: experiments, models, and mechanisms

FJ Vernerey, S Lalitha Sridhar, A Muralidharan… - Chemical …, 2021 - ACS Publications
Hydrogels are highly water-swollen molecular networks that are ideal platforms to create
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …

Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling

CM Madl, BL LeSavage, RE Dewi, CB Dinh… - Nature materials, 2017 - nature.com
Neural progenitor cell (NPC) culture within three-dimensional (3D) hydrogels is an attractive
strategy for expanding a therapeutically relevant number of stem cells. However, relatively …

Nanoarchitectonics beyond self‐assembly: challenges to create bio‐like hierarchic organization

K Ariga, X Jia, J Song, JP Hill… - Angewandte Chemie …, 2020 - Wiley Online Library
Incorporation of non‐equilibrium actions in the sequence of self‐assembly processes would
be an effective means to establish bio‐like high functionality hierarchical assemblies. As a …