When Szent-Györgyi called water the “matrix of life”, 1 he was echoing an old sentiment.
Paracelsus in the 16th century said that “water was the matrix of the world and of all its …

Liquid water is a highly versatile material. Although it is formed from the tiniest of molecules,
it can shape and control biomolecules. The hydrogen-bonding properties of water are …

One of the most exciting developments in the field of biological physics in recent years is the
ability to manipulate single molecules and probe their properties and function. Since its …

This work reviews the stripping off, role of water molecules in activity, and flexibility of
immobilized Candida antarctica lipase B (CALB). Employment of CALB in ring opening …

Background The structure and flexibility of Candida antarctica lipase B in water and five
different organic solvent models was investigated using multiple molecular dynamics …

Water in the proximity of a surface (interfacial water) is abundant on the earth. It is involved
in various physical and chemical processes and crucial for biological function. Despite …

Ultrafast two-dimensional infrared (2D-IR) spectroscopy reveals picosecond protein and
hydration dynamics of crowded hen egg white lysozyme (HEWL) labeled with a metal …

In the last three decades, protein and nucleic acid structure determination and
comprehension of the mechanisms, leading to their physiological and pathological …

The π electron cloud of aromatic centers is known to be involved in several noncovalent
interactions such as C H··· π, O H··· π, and π··· π interactions in biomolecules. Lone‐pair …

Proteins are key components of biological cells. For example, enzymes catalyze
biochemical reactions, membrane transporters are responsible for uptake and release of …