Dedifferentiation of myelinating Schwann cells is a key feature of nerve injury and
demyelinating neuropathies. We review recent evidence that this dedifferentiation depends …

Pathological pain conditions can be triggered after peripheral nerve injury and/or
inflammation. It is associated with plasticity of nociceptive pathway in which pain is …

Some Toll and Toll-like receptors (TLRs) provide immunity to experimental infections in
animal models, but their contribution to host defense in natural ecosystems is unknown. We …

We hypothesize that innate immune signals from infectious organisms and/or injured tissues
may activate peripheral neuronal pain signals. In this study, we demonstrated that TLRs 3, 7 …

Toll‐like receptors comprise a family of evolutionary conserved pattern recognition receptors
that act as a first defense line in the innate immune system. Upon stimulation with microbial …

Toll-like receptors (TLRs) are type I transmembrane signaling molecules that are expressed
in cells of the innate immune system. In these cells, TLRs function as pattern recognition …

The central nervous system (CNS) has very limited capacity to regenerate after traumatic
injury or disease. In contrast, the peripheral nervous system (PNS) has far greater capacity …

Background. Tick-borne encephalitis virus (TBEV) infections may be asymptomatic or cause
severe symptoms in the central nervous system. A mutation in the chemokine receptor 5 …

Neuronal toll-like receptors and neuro-immunity in Parkinson’s disease, Alzheimer’s disease
and stroke Page 1 27 © 2016 Neuroimmunology and Neuroinflammation | Published by OAE …

Toll‐like receptors (TLRs) have been shown to play an important role in the immune system,
which warrants study of their remarkable potential as pharmacological targets. Activation of …