In vivo near-infrared (NIR) fluorescence imaging is an emerging biomedical imaging
modality for use in both fundamental scientific research and clinical practice. Owing to …

Fluorescence imaging has made tremendous inroads toward understanding the complexity
of biological systems, but in vivo deep-tissue imaging remains a great challenge due to the …

Organic dye based NIR‐II fluorescent probes, owing to their high signal‐to‐background ratio
and deeper penetration, are highly useful for deep‐tissue high‐contrast imaging in vivo …

A small‐molecule fluorophore FD‐1080 with both excitation and emission in the NIR‐II
region has been successfully synthesized for in vivo imaging. A heptamethine structure is …

Intraoperative fluorescent imaging can provide real-time identification of tumours, lymph
nodes, nerves and other healthy and malignant tissues during oncological surgery …

Local recurrence is a common cause of treatment failure for patients with solid tumors.
Tumor-specific intraoperative fluorescence imaging may improve staging and debulking …

Organic fluorophores have been widely used for biological imaging in the visible and the
first near-infrared windows. However, their application in the second near-infrared window …

Surgical resection of cancer remains an important treatment modality. Despite advances in
preoperative imaging, surgery itself is primarily guided by the surgeon's ability to locate …

Paradigm shifts in surgery arise when surgeons are empowered to perform surgery faster,
better and less expensively than current standards. Optical imaging that exploits invisible …

Near‐infrared (NIR) fluorescence imaging is gaining clinical acceptance over the last years
and has been used for detection of lymph nodes, several tumor types, vital structures and …