Highlights•CD44 receptor is overexpressed in highly invasive stem-like cancer cells
(SLCS).•CD44 receptors have high affinity toward hyaluronic acid (HA) binding.•Recent …

We examined the pupicidal, adulticidal, repellent, and oviposition-deterrent activities of
essential oils (EOs) from Lippia alba, L. origanoides, Eucalyptus citriodora, Cymbopogon …

Rationale: Dimethyl sulfoxide (DMSO) is commonly used as a solvent for water-insoluble
substances, a vehicle for drug therapy, and a cryoprotectant for cultured cells. DMSO …

A tumor cell-targeted prodrug was developed for quercetin, using hyaluronic acid as
polymeric carrier. Hyaluronic acid-quercetin (HA-QT) bioconjugates were synthesized by …

Brine shrimp lethality bioassay is a simple, high throughput cytotoxicity test of bioactive
chemicals. It is based on the killing ability of test compounds on a simple zoological …

Inhibiting the activity of fatty-acid amide hydrolase (FAAH), the enzyme that deactivates the
endocannabinoid anandamide, enhances anandamide-mediated signaling and holds …

Messenger RNA (mRNA)-based therapies are a novel class of therapeutics used in
vaccination and protein replacement therapies for monogenic diseases. Previously, we …

Abstract N-methyl pyrrolidone (NMP), dimethyl sulfoxide (DMSO), 2-pyrrolidone (PYR) and
eutectic (1: 1 menthol: camphor) were used as solvents for bleached shellac in doxycycline …

Parkinson's disease (PD) is triggered by the formation of free radicals in dopaminergic
neurons, which results in oxidative stress-induced neurodegeneration. The objective of the …

Usnic acid (UA) has been used as an antitumor drug; however, its hepatotoxicity hinders its
therapeutic use. This study aimed to design a targeted nanocarrier loaded with UA for drug …