Recent review on selected xenobiotics and their impacts on gut microbiome and metabolome

Y Jin, J Chi, K LoMonaco, A Boon, H Gu - TrAC Trends in Analytical …, 2023 - Elsevier
As it is well known, the gut is one of the primary sites in any host for xenobiotics, and the
many microbial metabolites responsible for the interactions between the gut microbiome and …

Polybrominated diphenyl ethers (PBDEs) and human health: effects on metabolism, diabetes and cancer

V Renzelli, M Gallo, L Morviducci, G Marino, A Ragni… - Cancers, 2023 - mdpi.com
Simple Summary Endocrine disruptors are chemicals that can interfere and interact with the
endocrine system, resulting in altered hormonal signaling and function. PBDEs are common …

[HTML][HTML] Polybrominated diphenyl ether (PBDE) exposure and adverse maternal and infant health outcomes: systematic review

J Gomes, M Begum, P Kumarathasan - Chemosphere, 2024 - Elsevier
Polybrominated diphenyl ethers (PBDEs) are flame retardants found in ambient environment
and are measured in humans. There are reports on general PBDE toxicity, including …

The effect of endocrine-disrupting chemicals on placental development

Y Yan, F Guo, K Liu, R Ding, Y Wang - Frontiers in endocrinology, 2023 - frontiersin.org
Endocrine-disrupting chemicals (EDCs) or endocrine disruptors are substances that are
either naturally occurring or artificial and are released into the natural environment. Humans …

[HTML][HTML] Behavioral changes and transcriptomic effects at embryonic and post-embryonic stages reveal the toxic effects of 2, 2′, 4, 4′-tetrabromodiphenyl ether on …

S Zheng, Q Zhang, R Wu, X Shi, J Peng, W Tan… - Ecotoxicology and …, 2022 - Elsevier
Polybrominated biphenyl ethers (PBDEs) are new persistent pollutants that are widely exist
in the environment and have many toxic effects. However, their toxicity mechanisms on …

Prenatal exposure to polybrominated diphenyl ethers and birth outcomes

A Reddam, A Sjödin, W Cowell, R Jones, S Wang… - Environmental …, 2023 - Elsevier
Abstract Background Polybrominated diphenyl ethers (PBDEs) were used as flame
retardants and from their end-use products they can be released to accumulate within indoor …

A comprehensive multiplatform metabolomic analysis reveals alterations of 2-hydroxybutyric acid among women with deep endometriosis related to the pesticide trans …

T Lefebvre, M Campas, K Matta, S Ouzia… - Science of the Total …, 2024 - Elsevier
Background Exposure to persistent organic pollutants (POPs) has been related to the risk of
endometriosis however the mechanisms remain unclear. The objective of the present study …

Metabolomics perspectives into the co-exposure effect of polycyclic aromatic hydrocarbons and metals on renal function: A meet-in-the-middle approach

Q Liao, L Huang, F Cai, W Luo, M Li, J Yang… - Science of The Total …, 2024 - Elsevier
Studies on the dose effects of kidney impairment and metabolomes in co-exposure to
polycyclic aromatic hydrocarbons (PAHs) and metals are limited. We aimed to identify …

Long-term effect of PBDE-99 prenatal exposure on spermatogenic injuries via the dysregulation of autophagy

J Wu, F Deng, X Tang, W Chen, R Zhou, T Zhao… - Journal of Hazardous …, 2023 - Elsevier
Although it has been reported that perinatal, especially prenatal exposure to polybrominated
diphenyl ethers (PBDEs) alters offspring's fertility, but little is known regarding their …

A review of statistical strategies to integrate biomarkers of chemical exposure with biomarkers of effect applied in omic-scale environmental epidemiology

É Babin, G Cano-Sancho, E Vigneau… - Environmental Pollution, 2023 - Elsevier
Humans are exposed to a growing list of synthetic chemicals, some of them becoming a
major public health concern due to their capacity to impact multiple biological endpoints and …