Health beneficial and pharmacological properties of p-cymene

A Balahbib, N El Omari, NEL Hachlafi, F Lakhdar… - Food and Chemical …, 2021 - Elsevier
Abstract p-cymene also known as p-cymol or p-isopropyltoluene is an alkyl-substituted
aromatic compound naturally occurring in essential oils (EOs) of various aromatic plants …

Piano stool Ru (II)-arene complexes having three monodentate legs: A comprehensive review on their development as anticancer therapeutics over the past decade

S Swaminathan, J Haribabu, N Balakrishnan… - Coordination chemistry …, 2022 - Elsevier
The popularity of RAPTA-C in in vivo studies has steered the way for complexes of the type
[Ru (η 6-arene)(X)(Y)(Z)] n+ (where X, Y and Z are monodentate ligands) to be developed …

Synthesis of palladium (II) complexes via Michael addition: antiproliferative effects through ROS-mediated mitochondrial apoptosis and docking with SARS-CoV-2

J Haribabu, S Srividya, D Mahendiran… - Inorganic …, 2020 - ACS Publications
Metal complexes have numerous applications in the current era, particularly in the field of
pharmaceutical chemistry and catalysis. A novel synthetic approach for the same is always a …

Target based chemotherapeutic advancement of ruthenium complexes

BK Kundu, S Mukhopadhyay - Coordination Chemistry Reviews, 2021 - Elsevier
Over the last few years, great emphasis has been given to develop ruthenium complexes to
act as target specified chemotherapeutic agents. Indeed, there are few reviews available …

Novel tetranuclear ruthenium (II) arene complexes showing potent cytotoxic and antimetastatic activity as well as low toxicity in vivo

MKM Subarkhan, L Ren, B Xie, C Chen, Y Wang… - European journal of …, 2019 - Elsevier
Ruthenium complexes have attracted a surge of interest as anticancer drug candidates
because of their low toxicity, diversity in mode-of-actions and non-cross drug resistance with …

Synthesis, spectroscopic characterizations, single crystal X-ray analysis, DFT calculations, in vitro biological evaluation and in silico evaluation studies of …

VNV Palakkeezhillam, J Haribabu… - Journal of Molecular …, 2023 - Elsevier
We created new thiosemicarbazones and their cyclized heterocyclic compounds, examined
them, and evaluated their biological activity in silico and in vitro. Two pyrene-based …

Unprecedented formation of palladium (II)-pyrazole based thiourea from chromone thiosemicarbazone and [PdCl2 (PPh3) 2]: Interaction with biomolecules and …

J Haribabu, C Balachandran, MM Tamizh… - Journal of Inorganic …, 2020 - Elsevier
Two novel pyrazole based thiourea palladium (II) complexes,[PdCl (PPh 3)(C 9 H 8 NO 2 S-
pz)](1) and [PdCl (PPh 3)(C 14 H 10 NO 2 S-pz)](2)[pz= pyrazole (C 3 H 2 N 2)] have been …

Bidentate acylthiourea ligand anchored Pd-PPh3 complexes with biomolecular binding, cytotoxic, antioxidant and antihemolytic properties

DP Dorairaj, J Haribabu, PVS Shashankh… - Journal of Inorganic …, 2022 - Elsevier
Acylthiourea-based Pd (II) complexes (1–5) with a PPh 3 moiety bearing the general formula
[PdCl (PPh 3)(LR)][LR= monoanionic bidentate acylthiourea ligand, where R= C 6 H 5 (L1) …

Copper (II) complexes based on levofloxacin and 2N-donor ligands: synthesis, crystal structures and in vitro biological evaluation

M Kumar, G Kumar, KM Dadure… - New Journal of Chemistry, 2019 - pubs.rsc.org
Herein, we report the synthesis, molecular structures and bioevaluation of two different
cationic copper (II) complexes with the third generation quinolone antibacterial agent …

Enhanced anticancer activity of half-sandwich Ru (II)-p-cymene complex bearing heterocyclic hydrazone ligand

J Haribabu, S Srividya, R Umapathi, D Gayathri… - Inorganic Chemistry …, 2020 - Elsevier
The hydrazone ligand (HL) was synthesized from furan-2-carbohydrazide and indole-3-
carboxaldehyde. The reaction of [RuCl 2 (p-cymene)] 2 with HL in the presence of sodium …