Inflammasomes are multiprotein innate immune complexes that regulate caspase-
dependent inflammation and cell death. Pattern recognition receptors, such as nucleotide …

Cytoplasmic nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3)
forms an inflammasome with apoptosis-associated speck-like protein containing a CARD …

The pathogenetic mechanism of contrast-induced acute kidney injury (CI-AKI), which is the
third most common cause of hospital-acquired AKI, has not been elucidated. Previously, we …

Contrast-induced acute kidney injury (CI-AKI) occurs in more than 30% of patients after
intravenous iodinated contrast media and causes serious complications, including renal …

Trimethyltin chloride (TMT) is an organotin heat stabilizer that is widely used in the
production of plastics, and has strong toxicity. Here, the effect of trimethyltin chloride on …

Contrast-induced acute kidney injury (CI-AKI) is a serious complication in patients after
administration of iodinated contrast media and is associated with a significant high risk for …

Chronic inflammation might correlate with the formation of α-synuclein oligomers,
subsequently leading to dopaminergic (DA) neuronal death in Parkinson's disease (PD). As …

Inflammasomes, multiprotein complex induced by harmful factors in the body, play a crucial
role in innate immunity. Activation of inflammasomes lead to the activation of casepase-1 …

Radiographic contrast agents cause acute kidney injury (AKI), yet the underlying
pathogenesis is poorly understood. Nod-like receptor pyrin containing 3–deficient (Nlrp3 …

Contrast-induced acute kidney injury (CI-AKI) is a main cause of hospital-acquired renal
failure. Nevertheless, limited measures have been shown to be effective for the treatment of …