KH Parker, DW Beury, S Ostrand-Rosenberg - Advances in cancer …, 2015 - Elsevier
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells that suppress innate and adaptive immunity. MDSCs are present in many …
J Zhang, Z Hu, CA Horta, J Yang - Seminars in cancer biology, 2023 - Elsevier
Epithelial–mesenchymal transition (EMT) has been implicated in various aspects of tumor development, including tumor invasion and metastasis, cancer stemness, and therapy …
M von Locquenghien, C Rozalén… - The Journal of …, 2021 - Am Soc Clin Investig
Interferons (IFNs) are pleiotropic cytokines critical for regulation of epithelial cell functions and for immune system regulation. In cancer, IFNs contribute to tumor-intrinsic and-extrinsic …
Myeloid-derived suppressor cells (MDSCs) constitute a vast population of immature myeloid cells implicated in various conditions. Most notably, their role in cancer is of great …
C McElrath, V Espinosa, JD Lin, J Peng… - Nature …, 2021 - nature.com
The etiology of ulcerative colitis is poorly understood and is likely to involve perturbation of the complex interactions between the mucosal immune system and the commensal bacteria …
JS Park, SS Withers, JF Modiano, MS Kent… - … for immunotherapy of …, 2016 - Springer
Despite recent major clinical breakthroughs in human cancer immunotherapy including the use of checkpoint inhibitors and engineered T cells, important challenges remain, including …
H Zhu, Y Gu, Y Xue, M Yuan, X Cao, Q Liu - Oncotarget, 2017 - ncbi.nlm.nih.gov
Although myeloid-derived suppressor cells (MDSCs) have been demonstrated to contribute to tumor initiation, progression and metastasis, however, which MDSC subsets are …
L Jiang, Y Qi, L Yang, YB Miao, W Ren, H Liu… - Asian Journal of …, 2023 - Elsevier
How to effectively transform the pro-oncogenic tumor microenvironments (TME) surrounding a tumor into an anti-tumoral never fails to attract people to study. Small interfering RNA …
AR Pyzer, L Cole, J Rosenblatt… - International journal of …, 2016 - Wiley Online Library
The tumor microenvironment consists of an immunosuppressive niche created by the complex interactions between cancer cells and surrounding stromal cells. A critical …