The GATA family of transcription factors is of crucial importance during embryonic
development, playing complex and widespread roles in cell fate decisions and tissue …

The GATA family of transcription factors consists of six proteins (GATA1-6) which are
involved in a variety of physiological and pathological processes. GATA1/2/3 are required …

Congenital heart defects (CHDs) are the most common developmental anomaly and are the
leading non-infectious cause of mortality in newborns. Only one causative gene, NKX2-5 …

Six GATA transcription factors have been identified in vertebrates, each of which contains a
highly conserved DNA binding domain consisting of two zinc fingers of the motif Cys-X2-Cys …

Polycomb-repressive complex 2 (PRC2) promotes tissue-specific differentiation by
depositing trimethylated histone H3 Lys 27 (H3K27me3) epigenetic marks to silence ectopic …

During the past decade, emerging evidence has accumulated of different nuclear
transcription factors in regulation of cardiac development and growth as well as in cardiac …

The mechanisms regulating vertebrate heart and endoderm development have recently
become the focus of intense study. Here we present evidence from both loss-and gain-of …

Anautogeny is a successful reproductive strategy utilized by many mosquito species and
other disease-transmitting arthropod vectors. Developing an understanding of the …

Epithelial gene expression in the lung is thought to be regulated by the coordinate activity of
several different families of transcription factors including the Fox family of winged …

Abstract Foxp1, Foxp2, and Foxp4 are large multidomain transcriptional regulators
belonging to the family of winged-helix DNA binding proteins known as the Fox family …