Knowledge gaps that hamper prevention and control of Mycobacterium avium subspecies paratuberculosis infection

HW Barkema, K Orsel, SS Nielsen… - Transboundary and …, 2018 - Wiley Online Library
In the last decades, many regional and country‐wide control programmes for Johne's
disease (JD) were developed due to associated economic losses, or because of a possible …

Pathogenesis, Molecular Genetics, and Genomics of Mycobacterium avium subsp. paratuberculosis, the Etiologic Agent of Johne's Disease

G Rathnaiah, DK Zinniel, JP Bannantine… - Frontiers in veterinary …, 2017 - frontiersin.org
Mycobacterium avium subsp. paratuberculosis (MAP) is the etiologic agent of Johne's
disease in ruminants causing chronic diarrhea, malnutrition, and muscular wasting …

Identification of essential genes in Mycobacterium avium subsp. paratuberculosis genome for persistence in dairy calves

R Eshraghisamani, AJ Mirto, J Wang, MA Behr… - Frontiers in …, 2022 - frontiersin.org
To cause disease Mycobacterium avium subsp. paratuberculosis needs to enter mammalian
cells, arrest phagosomal maturation and manipulate the host immune system. The genetic …

Modeling Paratuberculosis in Laboratory Animals, Cells, or Tissues: A Focus on Their Applications for Pathogenesis, Diagnosis, Vaccines, and Therapy Studies

A Jolly, B Fernández, SL Mundo, N Elguezabal - Animals, 2023 - mdpi.com
Simple Summary Paratuberculosis is a chronic infectious disease that affects a wide variety
of domestic and wild animals. It is considered one of the diseases with the highest economic …

Mycobacterium avium subsp. paratuberculosis Candidate Vaccine Strains Are Pro-apoptotic in RAW 264.7 Murine Macrophages

RG Barletta, JP Bannantine, JR Stabel… - Vaccines, 2023 - mdpi.com
Mycobacterium avium subsp. paratuberculosis (MAP) is the etiological agent of Johne's
disease, a severe gastroenteritis of ruminants. This study developed a model cell culture …

Humoral and Cellular Immune Response of European Seabass Dicentrarchus labrax Vaccinated with Heat‐Killed Mycobacterium marinum (iipA::kan Mutant)

N Ziklo, A Colorni, LY Gao, SJ Du… - Journal of Aquatic …, 2018 - Wiley Online Library
No vaccine is yet commercially available against Mycobacterium marinum, the etiological
agent of fish mycobacteriosis (also known as “fish tuberculosis”). The mycobacterial gene …

Diversity of bacterial biofilm communities on sprinklers from dairy farm cooling systems in Israel

NY Shpigel, Z Pasternak, G Factor, Y Gottlieb - PLoS One, 2015 - journals.plos.org
On dairy farms in hot climates worldwide, cows suffer from heat stress, which is alleviated by
the use of water cooling systems. Sprinklers and showerheads are known to support the …

Isolation, Identification, and Characterization of a New Highly Pathogenic Field Isolate of Mycobacterium avium spp. avium

L Zhu, Y Peng, J Ye, T Wang, Z Bian, Y Qin… - Frontiers in veterinary …, 2018 - frontiersin.org
Avian tuberculosis is a chronic, contagious zoonotic disease affecting birds, mammals, and
humans. The disease is most often caused by Mycobacterium avium spp. avium (MAA) …

Controlling Johne's disease: vaccination is the way forward

JP Bannantine, AM Talaat - Frontiers in cellular and infection …, 2015 - frontiersin.org
M. avium subspecies paratuberculosis, hereafter referred to as MAP, is a significant
veterinary pathogen that causes Johne's disease in ruminants, including cattle, sheep, and …

Proteome-scale identification and characterization of mitochondria targeting proteins of Mycobacterium avium subspecies paratuberculosis: potential virulence factors …

A Rana, D Kumar, A Rub, Y Akhter - Mitochondrion, 2015 - Elsevier
Mycobacterium avium subsp. paratuberculosis is the etiological agent of Johne's Disease
among ruminants. During the course of infection, it expresses a number of proteins for its …