Oral submucous fibrosis and heterogeneity in outcome measures: a critical viewpoint

SC Sarode, S Gondivkar, A Gadbail, GS Sarode… - Future …, 2021 - Taylor & Francis
Conclusion We sense a dire need for consensus-based development of standardized
outcome measures for effective reporting of therapeutic efficacy in OSF patients. Equally …

Systemic and local effects among patients with betel quid-related oral cancer

HC Chuang, MH Tsai, YT Lin… - … in cancer research …, 2022 - journals.sagepub.com
The major predisposing factors of developing oral cancer include smoking, alcohol drinking,
and betel quid chewing. Betel quid chewing could cause the abrasion and damage of oral …

Do betel quid and areca nut chewing deteriorate prognosis of oral cancer? A systematic review, meta‐analysis, and research agenda

J Yang, ZY Wang, L Huang, TL Yu, SQ Wan… - Oral …, 2021 - Wiley Online Library
Objective To explore the correlations between the habit of betel quid and areca nut (BQ‐AN)
chewing and the prognosis of oral cancer (OC). Methods We performed a systematic review …

Oral cancer: Clinicopathological features and associated risk factors in a high risk population presenting to a major tertiary care center in Pakistan

N Anwar, S Pervez, Q Chundriger, S Awan, T Moatter… - Plos one, 2020 - journals.plos.org
Oral squamous cell carcinoma (OSCC) has the highest prevalence in head and neck
cancers and is the first and second most common cancer in males and females of Pakistan …

Spatial Transcriptomic and Metabolomic Landscapes of Oral Submucous Fibrosis‐Derived Oral Squamous Cell Carcinoma and its Tumor Microenvironment

Y Zhi, Q Wang, M Zi, S Zhang, J Ge, K Liu… - Advanced …, 2024 - Wiley Online Library
Abstract In South and Southeast Asia, the habit of chewing betel nuts is prevalent, which
leads to oral submucous fibrosis (OSF). OSF is a well‐established precancerous lesion, and …

[HTML][HTML] Prevalence of trismus and its impact on oral health-related quality of life in patients treated for oral squamous cell carcinoma

SM Gondivkar, AR Gadbail, SC Sarode… - Asian Pacific Journal …, 2021 - ncbi.nlm.nih.gov
Oral squamous cell carcinoma, one of the most common malignancies, has a poor
prognosis due to impairment in oral functions secondary to treatment. Trismus one of the …

Low-dose arecoline regulates distinct core signaling pathways in oral submucous fibrosis and oral squamous cell carcinoma

Z Li, Y Fu, Y Hu, Y Zhu, L Hu, C Shi, Y Zhang, J Zhang… - BMC Oral Health, 2023 - Springer
Background Betel nut chewing plays a role in the pathogenesis of oral submucous fibrosis
(OSF) and oral squamous cell carcinoma (OSCC). As the major active ingredient of the betel …

Oral submucous fibrosis stimulates invasion and epithelial‐mesenchymal transition in oral squamous cell carcinoma by activating MMP‐2 and IGF‐IR

PN Chen, CW Lin, SF Yang… - Journal of Cellular and …, 2021 - Wiley Online Library
Oral submucous fibrosis (OSF) involves a high risk of malignant transformation and has
been implicated in oral cancer. Limited studies have been conducted on the role of OSF in …

Oral submucous fibrosis as an overhealing wound: Implications in malignant transformation

M Sharma, SS Shetty… - Recent patents on anti …, 2018 - ingentaconnect.com
Background: Oral submucous fibrosis is an oral potentially malignant disorder with high
incidence of malignant transformation and rising global prevalence. However, the genesis of …

CD1a+ and CD207+ cells are reduced in oral submucous fibrosis and oral squamous cell carcinoma

LC da Silva, FP Fonseca… - … Oral, Patología Oral …, 2019 - pmc.ncbi.nlm.nih.gov
Background The objective of this study investigated the distribution of immature dendritic
cells (DCs), Langerhans cells and plasmacytoid DCs in oral submucous fibrosis (OSMF) …