The stereotyped spatial architecture of the brain is both beautiful and fundamentally related
to its function, extending from gross morphology to individual neuron types, where soma …

The recent construction of brain-wide gene expression atlases, which measure the
transcriptional activity of thousands of genes in multiple anatomical locations, has made it …

To facilitate scalable profiling of single cells, we developed split-pool ligation-based
transcriptome sequencing (SPLiT-seq), a single-cell RNA-seq (scRNA-seq) method that …

Nervous systems are composed of various cell types, but the extent of cell type diversity is
poorly understood. We constructed a cellular taxonomy of one cortical region, primary visual …

Brain maps are essential for integrating information and interpreting the structure-function
relationship of circuits and behavior. We aimed to generate a systematic classification of the …

Spatial transcriptomics enables the simultaneous measurement of morphological features
and transcriptional profiles of the same cells or regions in tissues. Here we present multi …

Neuroanatomically precise, genome-wide maps of transcript distributions are critical
resources to complement genomic sequence data and to correlate functional and genetic …

Recent transcriptome analyses have revealed that noncoding RNAs (ncRNAs) are broadly
expressed in mammalian cells and abundant in the CNS, with tissue and cell type-specific …

Non-pial neocortical astrocytes have historically been thought to comprise largely a
nondiverse population of protoplasmic astrocytes. Here we show that astrocytes of the …

Clarifying gene expression in narrowly defined neuronal populations can provide insight
into cellular identity, computation, and functionality. Here, we used next-generation RNA …