Adherens junctions: from molecules to morphogenesis

TJC Harris, U Tepass - Nature reviews Molecular cell biology, 2010 - nature.com
How adhesive interactions between cells generate and maintain animal tissue structure
remains one of the most challenging and long-standing questions in cell and developmental …

The cell-cell adhesion molecule E-cadherin

F Van Roy, G Berx - Cellular and molecular life sciences, 2008 - Springer
This review is dedicated to E-cadherin, a calcium-dependent cell-cell adhesion molecule
with pivotal roles in epithelial cell behavior, tissue formation, and suppression of cancer. As …

Structures of the eukaryotic ribosome and its translational states in situ

PC Hoffmann, JP Kreysing, I Khusainov… - Nature …, 2022 - nature.com
Ribosomes translate genetic information into primary structure. During translation, various
cofactors transiently bind to the ribosome that undergoes prominent conformational and …

Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease

CT Ellebrecht, VG Bhoj, A Nace, EJ Choi, X Mao… - Science, 2016 - science.org
Ideally, therapy for autoimmune diseases should eliminate pathogenic autoimmune cells
while sparing protective immunity, but feasible strategies for such an approach have been …

Laminins in basement membrane assembly

E Hohenester, PD Yurchenco - Cell adhesion & migration, 2013 - Taylor & Francis
The heterotrimeric laminins are a defining component of all basement membranes and self-
assemble into a cell-associated network. The three short arms of the cross-shaped laminin …

Outcome of the first electron microscopy validation task force meeting

R Henderson, A Sali, ML Baker, B Carragher… - Structure, 2012 - cell.com
This Meeting Review describes the proceedings and conclusions from the inaugural
meeting of the Electron Microscopy Validation Task Force organized by the Unified Data …

Cryo-electron tomography: the challenge of doing structural biology in situ

V Lučić, A Rigort, W Baumeister - Journal of Cell Biology, 2013 - rupress.org
Electron microscopy played a key role in establishing cell biology as a discipline, by
producing fundamental insights into cellular organization and ultrastructure. Many seminal …

Dynamo: a flexible, user-friendly development tool for subtomogram averaging of cryo-EM data in high-performance computing environments

D Castaño-Díez, M Kudryashev, M Arheit… - Journal of structural …, 2012 - Elsevier
Dynamo is a new software package for subtomogram averaging of cryo Electron
Tomography (cryo-ET) data with three main goals: first, Dynamo allows user-transparent …

The intercalated disc: a unique organelle for electromechanical synchrony in cardiomyocytes

MS Nielsen, CJM van Opbergen… - Physiological …, 2023 - journals.physiology.org
The intercalated disc (ID) is a highly specialized structure that connects cardiomyocytes via
mechanical and electrical junctions. Although described in some detail by light microscopy …

Structure and biochemistry of cadherins and catenins

L Shapiro, WI Weis - Cold Spring Harbor perspectives in …, 2009 - cshperspectives.cshlp.org
Classical cadherins mediate specific adhesion at intercellular adherens junctions.
Interactions between cadherin ectodomains from apposed cells mediate cell–cell contact …