Biomolecular condensates, membrane-less entities arising from liquid–liquid phase
separation, hold dichotomous roles in health and disease. Alongside their physiological …

It is a sad fact that despite being almost completely preventable through human
papillomavirus (HPV) vaccination and screening, cervical cancer remains the fourth most …

Importance In recurrent human papilloma virus (HPV)–driven cancer, immune checkpoint
blockade with anti–programmed cell death 1 (PD-1) antibodies produces tumor regression …

Immunotherapy using dendritic cell (DC)-based vaccination is an approved approach for
harnessing the potential of a patient's own immune system to eliminate tumor cells in …

Cancer immunotherapy has recently gained much attention in the search of cancer cure due
to its ability to “train” the immune system in seeking out and removing residual tumor cells …

Immunotherapy has clinical activity in certain virally associated cancers. However, the tumor
antigens targeted in successful treatments remain poorly defined. We used a personalized …

Background Vulvar intraepithelial neoplasia is a chronic disorder caused by high-risk types
of human papillomavirus (HPV), most commonly HPV type 16 (HPV-16). Spontaneous …

To understand why cancer vaccine–induced T cells often do not eradicate tumors, we
studied immune responses in mice vaccinated with gp100 melanoma peptide in incomplete …

Human papillomavirus (HPV)-related malignancies are responsible for almost all cases of
cervical cancer in women, and over 50% of all cases of head and neck carcinoma …

Cancer vaccines are designed to promote tumor specific immune responses, particularly
cytotoxic CD8 positive T cells that are specific to tumor antigens. The earliest vaccines …