Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

Privileged structures have been widely used as an effective template for the research and
discovery of high value chemicals. Coumarin is a simple scaffold widespread in Nature and …

Light is a particularly appealing tool for on‐demand drug delivery due to its noninvasive
nature, ease of application, and exquisite temporal and spatial control. Great progress is …

Biological signalling is regulated through a complex and tightly choreographed interplay
between cells and their extracellular matrix. The spatiotemporal control of these interactions …

Biological processes are naturally regulated with high spatial and temporal control, as is
perhaps most evident in metazoan embryogenesis. Chemical tools have been extensively …

Photoactivated materials have found widespread use in biological and medical applications
and are playing an increasingly important role in the nascent field of three-dimensional (3D) …

Coumarins fused with other aromatic units have recently emerged as a hot topic of research.
Their synthesis is partly based on classical methodologies such as Pechmann reaction or …

The possibility offered by photocontrolling the activity of biomolecules in vivo while recording
physiological parameters is opening up new opportunities for the study of physiological …

Easily accessible green-light activatable (> 500 nm) photocages based on red-shifted, π-
extended coumarin scaffolds are developed with uncaging efficiencies similar to those of …

A new class of coumarin photocaging groups modified with an electron‐rich styryl moiety at
the 3‐position was constructed. The large π‐conjugated structure and stabilization of the …