Cancer risk of low dose ionizing radiation

YF Ali, FA Cucinotta, L Ning-Ang, G Zhou - Frontiers in Physics, 2020 - frontiersin.org
The radiation exposure of individuals has been on the rise due to an increased amount of
radiation use, eg, in medicine for diagnostic imaging and treatment procedures, industrial …

Modeling sarcomagenesis using multipotent mesenchymal stem cells

R Rodriguez, R Rubio, P Menendez - Cell research, 2012 - nature.com
Because of their unique properties, multipotent mesenchymal stem cells (MSCs) represent
one of the most promising adult stem cells being used worldwide in a wide array of clinical …

Long-term cultures of bone marrow–derived human mesenchymal stem cells frequently undergo spontaneous malignant transformation

GV Røsland, A Svendsen, A Torsvik, E Sobala… - Cancer research, 2009 - AACR
Human mesenchymal stem cells (hMSC) aid in tissue maintenance and repair by
differentiating into specialized cell types. Due to this ability, hMSC are currently being …

Long-term culture of mesenchymal stem cells impairs ATM-dependent recognition of DNA breaks and increases genetic instability

D Hladik, I Höfig, U Oestreicher, J Beckers… - Stem cell research & …, 2019 - Springer
Abstract Background Mesenchymal stem cells (MSCs) are attracting increasing interest for
cell-based therapies, making use of both their immuno-modulating and regenerative …

New insights into the understanding of mechanisms of radiation-induced heart disease

KX Wang, C Ye, X Yang, P Ma, C Yan, L Luo - Current Treatment Options …, 2023 - Springer
Opinion statement Cancer patients who receive high-dose thoracic radiotherapy may
develop radiation-induced heart disease (RIHD). The clinical presentation of RIHD …

The load of short telomeres, estimated by a new method, Universal STELA, correlates with number of senescent cells

L Bendix, PB Horn, UB Jensen, I Rubelj, S Kolvraa - Aging cell, 2010 - Wiley Online Library
Short telomeres are thought to trigger senescence, most likely through a single–or a group
of few–critically shortened telomeres. Such short telomeres are thought to result from a …

Chemopreventive properties of indole-3-carbinol, diindolylmethane and other constituents of cardamom against carcinogenesis

A Acharya, I Das, S Singh… - Recent patents on food …, 2010 - ingentaconnect.com
Oxidative stress results from an imbalance in the production of reactive oxygen species
(ROS) and cell's own antioxidant defenses that in part lead to numerous carcinogenesis …

[HTML][HTML] Mesenchymal stem cells, cancer challenges and new directions

N Serakinci, U Fahrioglu, R Christensen - European Journal of Cancer, 2014 - Elsevier
Therapeutic use of multipotent mesenchymal stromal stem cells (MSC) is a promising venue
for a large number of degenerative diseases and cancer. Their availability from many …

[HTML][HTML] The role of mesenchymal stem/progenitor cells in sarcoma: update and dispute

J Yang, Z Ren, X Du, M Hao, W Zhou - Stem cell investigation, 2014 - ncbi.nlm.nih.gov
Sarcoma is the collective name for a relatively rare, yet heterogeneous group of cancers,
most probably derived from mesenchymal tissues. There are currently over 50 sarcoma …

ICRP publication 131: stem cell biology with respect to carcinogenesis aspects of radiological protection

O Niwa, MH Barcellos-Hoff, RK Globus… - Annals of the …, 2015 - journals.sagepub.com
This report was prepared by a task group of International Commission on Radiological
Protection (ICRP) Committee 1 under the following terms of reference:(a) to review stem cell …