▪ Abstract Proteins that contain the Arg-Gly-Asp (RGD) attachment site, together with the
integrins that serve as receptors for them, constitute a major recognition system for cell …

Fibronectin (FN) is a multidomain protein with the ability to bind simultaneously to cell
surface receptors, collagen, proteoglycans, and other FN molecules. Many of these domains …

Load-bearing tissues, such as muscle and cartilage, exhibit high elasticity, high toughness
and fast recovery, but have different stiffness (with cartilage being significantly stiffer than …

The crystal structure of recombinant wild-type green fluorescent protein (GFP) has been
solved to a resolution of 1.9 Å by multiwavelength anomalous dispersion phasing methods …

X-ray crystallography is an established method for studying the structure of proteins and
other macromolecules. As the importance of proteins grows, researchers in many fields have …

Living things are unimaginably complex, yet they have withstood a withering assault of
harmful influences over several billion years. These influences include cataclysmic changes …

The fibronectin type III domain (FN3) is a small autonomous folding unit which occurs in
many animal proteins involving in ligand binding. The β-sandwich structure of FN3 closely …

Since the first crystal structure of an immunoglobulin revealed a modular architecture, the
characteristic β-sheet fold of the immunoglobulin domain has been found in many other …

The targeting of molecular repertoires to complex systems rather than biochemically pure
entities is an accessible approach that can identify proteins of biological interest. We have …

The determination of animal form depends on the coordination of events that lead to the
morphological patterning of cells. This epigenetic view of development suggests that …