Prognostic and diagnostic values of non-coding RNAs as biomarkers for breast cancer: An umbrella review and pan-cancer analysis

A Bahramy, N Zafari, F Rajabi, A Aghakhani… - Frontiers in Molecular …, 2023 - frontiersin.org
Background: Breast cancer (BC) is the most common cancer in women. The incidence and
morbidity of BC are expected to rise rapidly. The stage at which BC is diagnosed has a …

The diagnostic and prognostic role of miR-27a in cancer

W Bi, J Li, M Xiong, B Pan, Z Zhang, L Nasifu… - … -Research and Practice, 2023 - Elsevier
Abstract MicroRNA-27a (miR-27a) has been reported to be abnormally expressed in
patients with cancer, and it could play potential roles as a diagnostic and prognostic …

Regulation and tumor‐suppressive function of the miR‐379/miR‐656 (C14MC) cluster in cervical cancer

S Srinath, PV Jishnu, VK Varghese, V Shukla… - Molecular …, 2024 - Wiley Online Library
Cervical cancer (CC) is a key contributor to cancer‐related mortality in several countries.
The identification of molecular markers and the underlying mechanism may help improve …

Cooperative miRNA-dependent PTEN regulation drives resistance to BTK inhibition in B-cell lymphoid malignancies

I Kapoor, J Bodo, BT Hill, A Almasan - Cell death & disease, 2021 - nature.com
Aberrant microRNA (miR) expression plays an important role in pathogenesis of different
types of cancers, including B-cell lymphoid malignancies and in the development of chemo …

CircRNA hsa_circ_0070659 predicts poor prognosis and promotes non-small cell lung cancer (NSCLC) progression via microRNA-377 (miR-377)/Ras-Associated …

Q Meng, Y Li, Z Sun, X Yang - Bioengineered, 2022 - Taylor & Francis
ABSTRACT A large number of circular RNAs (circRNAs) are dysregulated in lung cancer
and affect the progression and prognosis of lung disease. Herein, this study selected …

Reciprocal regulation between DNMT3A/3B and microRNAs miRs-299-3p/-30e is a causal factor for the downregulation of microRNAs targeting Androgen Receptor in …

K Ganapathy, CF Harrs, S Harris, SJ Staklinski… - Heliyon, 2025 - cell.com
Background Promoter hypermethylation is one of the events that downregulate microRNAs
(miRNA), resulting in the differential expression of genes implicated in the progression of …

Effects of selective inhibition of prostaglandin E2 receptors EP2 and EP4 on the miRNA profile in endometriosis

JA Arosh, KK Sivakumar, JH Lee, SK Banu - Molecular and cellular …, 2022 - Elsevier
Endometriosis is an estrogen-dependent, progesterone-resistant, chronic inflammatory
gynecological disease of reproductive-age women. Two major clinical symptoms of …

Essential role of the 14q32 encoded miRNAs in endocrine tumors

L Krokker, A Patócs, H Butz - Genes, 2021 - mdpi.com
Background: The 14q32 cluster is among the largest polycistronic miRNA clusters. miRNAs
encoded here have been implicated in tumorigenesis of multiple organs including endocrine …

[HTML][HTML] CircSOX9 acts as a molecular sponge of miR-485-3p to promote the progression of nasopharyngeal carcinoma

Y Sun, Y Liu, Z Du, L Zhou, Q Chen, H Chu - Aging (Albany NY), 2022 - ncbi.nlm.nih.gov
Circular RNA (circRNA) plays a vital role in the occurrence and development of
nasopharyngeal carcinoma (NPC). However, the role of certain specific circRNAs in NPC …

Emerging evidence of the functional impact of the miR379/miR656 cluster (C14MC) in breast cancer

EC McCarthy, RM Dwyer - Biomedicines, 2021 - mdpi.com
Many microRNAs exist in clusters that share comparable sequence homology and may
target genes in a common pathway. The miR-379/miR-656 (C14MC) cluster is imprinted in …