Despite the long held hypothesis that oxidant stress results in accumulated oxidative
damage to cellular macromolecules and subsequently to aging and age-related chronic …

The comet assay is the method of choice for measuring DNA damage, of various sorts, in
human cells such as lymphocytes obtained in the course of population-based studies of …

Within the last decade, the comet assay has been used with increasing popularity to
investigate the level of DNA damage in terms of strand breaks and alkaline labile sites in …

Human biomonitoring using the single cell gel electrophoresis (SCGE) or comet assay is a
novel approach for the assessment of genetic damage in exposed populations. This assay …

Biomonitoring of human populations exposed to potential mutagens or carcinogens can
provide an early detection system for the initiation of cell disregulation in the development of …

Genotoxicity measured by the comet assay is expressed by different researchers using
parameters that are not easy to conceptualize, except for percent tail DNA (% T) or visual …

Single cell gel electrophoresis, also known as the comet assay, is widely used for the
detection and measurement of DNA strand breaks. With the addition of a step in which DNA …

The alkaline single-cell microgel-electrophoresis ('comet') assay, allowing the evaluation of
damage occurring at the DNA level in individual cells associated with exposure to genotoxic …

The mutagenic and carcinogenic effects of genotoxic agents on exposed people have
constituted an increasing concern. Therefore, the objective of this work was to assess DNA …

Silica nanoparticles have an interesting potential in drug delivery, gene therapy and
molecular imaging due to the possibility of tailoring their surface reactivity that can be …