Although skeletal muscle repairs itself following small injuries, genetic diseases or severe
damages may hamper its ability to do so. Induced pluripotent stem cells (iPSCs) can …

Advanced in vitro models of human skeletal muscle tissue are increasingly needed to model
complex developmental dynamics and disease mechanisms not recapitulated in animal …

Traumatic injuries, tumor resections, and degenerative diseases can damage skeletal
muscle and lead to functional impairment and severe disability. Skeletal muscle …

Recent years have witnessed significant progress in skeletal muscle tissue regeneration.
Numerous bioengineering approaches have been implemented to construct in vitro skeletal …

Recently, skeletal muscle represents a complex and challenging tissue to be generated in
vitro for tissue engineering purposes. Several attempts have been pursued to develop …

The neuromuscular junction (NMJ) is a specialized cholinergic synaptic interface between a
motor neuron and a skeletal muscle fiber that translates presynaptic electrical impulses into …

The in vitro generation of human cardiomyocytes derived from induced pluripotent stem cells
(iPSC) is of great importance for cardiac disease modeling, drug-testing applications and for …

Single-cell patterning technologies are rapidly evolving, where single cells are positioned in
spatially distinct areas, thus providing a platform for several biological and biomedical …

Currently, the fabrication of scaffolds for engineered skeletal muscle tissues is unable to
reach the millimeter size. The main drawbacks are the poor nutrient diffusion, lack of an …

Lineage-specific differentiation of human induced pluripotent stem cells (hiPSCs) relies on
complex interactions between biochemical and physical cues. Here we investigated the …