The identification of high-risk human papillomavirus (HPV) types as a necessary cause of
cervical cancer offers the prospect of effective primary prevention and the possibility of …

The papillomavirus E2 proteins are pivotal to the viral life cycle and have well characterized
functions in transcriptional regulation, initiation of DNA replication and partitioning the viral …

Sexually transmitted carcinogenic human papillomavirus (HPV) infections are extraordinarily
prevalent worldwide. However, most incident HPV infections clear within a few years …

Abstract Human Papillomaviruses (HPVs) are double-stranded DNA viruses, that infect
epithelial cells and are etiologically involved in the development of human cancer. Today …

While organized screening programs in industrialized countries have significantly reduced
cervical cancer incidence, cytology-based screening has several limitations. Equivocal or …

The clearly higher sensitivity and reproducibility of human papillomavirus (HPV) DNA testing
for high-grade cervical intraepithelial neoplasia (CIN) has led to widespread calls to …

Background Persistent infections with carcinogenic human papillomavirus (HPV) types are
the necessary cause of cervical cancer. We recently demonstrated that the HPV16 genome …

Cervical cancer is the most prevalent gynecologic malignancy, especially in women of low-
and middle-income countries (LMICs). With a better understanding of the etiology and …

Approximately 15–20% of human cancers are caused by viruses, including human
papillomaviruses (HPVs). Viruses are obligatory intracellular parasites and encode proteins …

Human papilllomaviruses (HPVs) are common human pathogens that infect cutaneous or
mucosal epithelia in which they cause warts, self-contained benign lesions that commonly …