Hyperoside: A review on its sources, biological activities, and molecular mechanisms

Q Wang, HC Wei, SJ Zhou, Y Li, TT Zheng… - Phytotherapy …, 2022 - Wiley Online Library
Hyperoside is a natural flavonol glycoside in various plants, such as Crataegus pinnatifida
Bge, Forsythia suspensa, and Cuscuta chinensis Lam. Medical research has found that …

Hypoxia-driven effects in cancer: characterization, mechanisms, and therapeutic implications

R Shi, C Liao, Q Zhang - Cells, 2021 - mdpi.com
Hypoxia, a common feature of solid tumors, greatly hinders the efficacy of conventional
cancer treatments such as chemo-, radio-, and immunotherapy. The depletion of oxygen in …

Hyperoside induces breast cancer cells apoptosis via ROS-mediated NF-κB signaling pathway

J Qiu, T Zhang, X Zhu, C Yang, Y Wang… - International Journal of …, 2019 - mdpi.com
Hyperoside (quercetin 3-o-β-d-galactopyranoside) is one of the flavonoid glycosides with
anti-inflammatory, antidepressant, and anti-cancer effects. But it remains unknown whether it …

Suppression of 6-hydroxydopamine-induced oxidative stress by hyperoside via activation of Nrf2/HO-1 signaling in dopaminergic neurons

SH Kwon, SR Lee, YJ Park, M Ra, Y Lee… - International journal of …, 2019 - mdpi.com
In our ongoing research to discover natural products with neuroprotective effects,
hyperoside (quercetin 3-O-galactoside) was isolated from Acer tegmentosum, which has …

NF-κB in pancreatic cancer: Its key role in chemoresistance

Q Li, G Yang, M Feng, S Zheng, Z Cao, J Qiu, L You… - Cancer letters, 2018 - Elsevier
Pancreatic cancer is considered a lethal disease with a high mortality and an extremely low
five-year survival rate. Chemotherapy plays a pivotal role in pancreatic cancer treatment …

Antioxidant Activity Evaluation of Dietary Flavonoid Hyperoside Using Saccharomyces Cerevisiae as a Model

Y Gao, L Fang, X Wang, R Lan, M Wang, G Du… - Molecules, 2019 - mdpi.com
Oxidative stress leads to various diseases, including diabetes, cardiovascular diseases,
neurodegenerative diseases, and even cancer. The dietary flavonol glycoside, hyperoside …

[HTML][HTML] Role of Notch signaling pathway in pancreatic cancer

J Gao, B Long, Z Wang - American journal of cancer research, 2017 - ncbi.nlm.nih.gov
Pancreatic cancer (PC) is one of the highly aggressive malignancies in the United States. It
has been shown that multiple signaling pathways are involved in the pathogenesis of PC …

Phytol and heptacosane are possible tools to overcome multidrug resistance in an in vitro model of acute myeloid leukemia

M Labbozzetta, P Poma, M Tutone, JA McCubrey… - Pharmaceuticals, 2022 - mdpi.com
Drug resistance is the ability of cancer cells to gain resistance to both conventional and
novel chemotherapy agents, and remains a major problem in cancer therapy. Resistance …

Traditional Chinese medicine may be further explored as candidate drugs for pancreatic cancer: a review

Y Gao, S Chen, J Sun, S Su, D Yang… - Phytotherapy …, 2021 - Wiley Online Library
Pancreatic cancer is a disease with a high mortality rate. Although survival rates for different
types of cancers have improved in recent years, the five‐year survival rate of pancreatic …

Administration with hyperoside sensitizes breast cancer cells to paclitaxel by blocking the TLR4 signaling

T Sun, Y Liu, M Li, H Yu, H Piao - Molecular and cellular probes, 2020 - Elsevier
Breast cancer is a malignancy and one of the most frequent causes of cancer death among
women worldwide. Paclitaxel is a common chemotherapeutic drug and has recently been …