Epigenetics regulates gene expression and has been confirmed to play a critical role in a
variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease …

Osteoporosis is a common metabolic bone disease, influenced by genetic and
environmental factors, that increases bone fragility and fracture risk and, therefore, has a …

Osteoporosis is a bone metabolic disease characterized by reduced bone mass and
deterioration of bone tissue microarchitecture, leading to enhanced skeletal fragility and …

Long noncoding RNAs are widely implicated in diverse disease processes. Nonetheless,
their regulatory roles in bone resorption are undefined. Here, we identify lncRNA Nron as a …

Osteoporosis is a systemic disease that results in loss of bone density and increased
fracture risk, particularly in the vertebrae and the hip. This condition and associated …

Bone metabolism consists of a balance between bone formation and bone resorption, which
is mediated by osteoblast and osteoclast activity, respectively. In order to ensure bone …

The switch between osteogenic and adipogenic differentiation of bone marrow
mesenchymal stem cells (BMSCs) plays a key role in aging-induced osteoporosis. In this …

Background Osteoporosis is a widespread and serious metabolic bone disease. At present,
revealing the molecular mechanisms of osteoporosis and developing effective prevention …

Calcium channel TRPV6 upregulation is associated with poor prognosis of breast cancer by
promoting invasion and metastasis, and TRPV6 is a potential target for breast cancer …

Bone is a mechanosensitive organ that provides strength and support. Many bone cells,
various pathways, and signaling molecules coordinate bone metabolism and also determine …