[HTML][HTML] Impella 5.5 versus Centrimag: a head-to-head comparison of device hemocompatibility

Y Roka-Moiia, M Li, A Ivich, S Muslmani, KB Kern… - Asaio …, 2020 - journals.lww.com
Despite growing use of mechanical circulatory support, limitations remain related to
hemocompatibility. Here, we performed a head-to-head comparison of the …

Study on the hemodynamic effects of different pulsatile working modes of a rotary blood pump using a microfluidic platform that realizes in vitro cell culture effectively

L Liang, X Wang, D Chen, P Sethu, GA Giridharan… - Lab on a Chip, 2024 - pubs.rsc.org
Rotary blood pumps (RBPs) operating at a constant speed generate non-physiologic blood
pressure and flow rate, which can cause endothelial dysfunction, leading to adverse clinical …

Resistance valves in circulatory loops have a significant impact on in vitro evaluation of blood damage caused by blood pumps: a computational study

P Wu, Y Bai, G Du, L Zhang, X Zhao - Frontiers in Physiology, 2023 - frontiersin.org
Background: Hemolysis and its complications are major concerns during the clinical
application of blood pumps. In-vitro circulatory testing loops have been employed as the key …

Preclinical evaluation

AF Stephens, LP Wittberg, S Jacobs… - … and Respiratory Support, 2025 - Elsevier
Mechanical circulatory and respiratory support systems are classified as high-risk devices
that support or sustain human life by regulatory authorities worldwide and, as such, are …

A multi-constituent model for assessing the effect of impeller shroud on the thrombosis potential of a centrifugal blood pump

S Lv, ZP He, GM Liu, SS Hu - The International Journal of …, 2024 - journals.sagepub.com
Centrifugal blood pumps can be used for treating heart failure patients. However, pump
thrombosis has remained one of the complications that trouble clinical treatment. This study …

Computational modelling of blood flow in medical assist devices

F Fiusco - 2023 - diva-portal.org
Extracorporeal membrane oxygenation (ECMO) is a life-saving support treatment in case of
pulmonary and/or cardiac failure. An artificial extracorporeal circuit is used to offload the …

Design, modeling, and experimental characterization of a valveless pulsatile flow mechanical circulatory support device

M Li, Y Chen, MJ Slepian… - Journal of …, 2021 - asmedigitalcollection.asme.org
Mechanical circulatory support (MCS) devices, ie, ventricular assist devices (VADs) and total
artificial hearts (TAHs), while effective and vital in restoring hemodynamics in patients with …

Design and evaluation of a pulsatile flow rotary vane blood pump

M Li - Proceedings of the Institution of Mechanical Engineers …, 2023 - journals.sagepub.com
Artificial cardiovascular organs, termed as mechanical circulatory support (MCS) devices,
provide patients with hemodynamics circulatory restoration effectively and vitally but yet are …

[HTML][HTML] 动脉内皮血流动力学微环境建模分析和体外模拟方法与技术研究进展

覃开蓉, 梁夫友, 那景童 - 实验流体力学, 2020 - pubs.cstam.org.cn
动脉内皮微环境中的血压, 壁面剪应力和牵张应力等血流动力学参量在维持内皮的正常生理功能
中扮演着至关重要的角色. 在体(in vivo) 动脉内皮血流动力学微环境的建模分析与体外(in vitro) …

Valveless devices for pulsatile fluid flow

MJ Slepian, EJ Barth, M Li - US Patent App. 18/041,656, 2024 - Google Patents
TZCPCKNHXULUIY-RGULYWFUSA-N 1, 2-distearoyl-sn-glycero-3-phosphoserine
Chemical compound CCCCCCCCCCCCCCCCCC (= O) OC [C@ H](COP (O)(= O) OC [C …