Cuticular hydrocarbons (CHCs) have two fundamental functions in insects. They protect
terrestrial insects against desiccation and serve as signaling molecules in a wide variety of …

The organs and metabolic pathways involved in energy metabolism, and the process of ATP
production from nutrients, are comparable between humans and Drosophila melanogaster …

Peroxisomes are key regulators of cellular and metabolic homeostasis. These organelles
play important roles in redox metabolism, the oxidation of very-long-chain fatty acids …

Social isolation negatively affects health, induces detrimental behaviors, and shortens
lifespan in social species. Little is known about the mechanisms underpinning these effects …

Autophagy ensures the lysosome-mediated breakdown and recycling of self-material, as it
not only degrades obsolete or damaged intracellular constituents but also provides building …

The AAA-ATPases Pex1 and Pex6 are required for the formation and maintenance of
peroxisomes, membrane-bound organelles that harbor enzymes for specialized metabolism …

Despite recent advances in single-cell genomics, the lack of maps for single-cell candidate
cis-regulatory elements (cCREs) in non-mammal species has limited our exploration of …

Ecdysteroids are polyhydroxylated sterols, and are widespread in the plant and animal
world. To date, over 520 ecdysteroids have been isolated from natural sources. The most …

Animal experimentation is limited by unethical procedures, time-consuming protocols, and
high cost. Thus, the development of innovative approaches for disease treatment based on …

FOXO transcription factors have long been associated with longevity control and tissue
homeostasis. Although the transcriptional regulation of FOXO have been previously …