The stem cell/material interface is a complex, dynamic microenvironment in which the cell
and the material cooperatively dictate one another's fate: the cell by remodelling its …

Tissue engineering and its clinical application, regenerative medicine, are instructing
multiple approaches to aid in replacing bone loss after defects caused by trauma or cancer …

Biomaterial scaffolds mimicking the environment in metastatic organs can deconstruct
complex signals and facilitate the study of cancer progression and metastasis. Here we …

Current in vitro hematopoiesis models fail to demonstrate the cellular diversity and complex
functions of living bone marrow; hence, most translational studies relevant to the …

The current knowledge of bone marrow mechanics is limited to its viscous properties,
neglecting the elastic contribution of the extracellular matrix. To get a more complete view of …

Embryonic development, lengthening, and repair of most bones proceed by endochondral
ossification, namely through formation of a cartilage intermediate. It was previously …

Vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) have
been widely used in the fields of tissue engineering and regenerative medicine to stimulate …

To comprehend the complexity of cancer, the biological characteristics acquired during the
initiation and progression of tumours were classified as the'hallmarks of cancer'. Intravital …

Regenerative medicine technologies rely heavily on the use of well‐designed biomaterials
for therapeutic applications. The success of implantable biomaterials hinges upon the ability …

The skeleton is a unique structure capable of providing support for the body. Bone
resorption and deposition are controlled in a tightly regulated balance between osteoblasts …