Laboratory mice, rats, and rabbits may harbor a variety of viral, bacterial, parasitic, and
fungal agents. Frequently, these organisms cause no overt signs of disease. However, many …

Recirculating virgin CD4+ T cells spend their life migrating between the T zones of
secondary lymphoid tissues where they screen the surface of interdigitating dendritic cells. T …

Two novel exogenous mouse mammary tumor viruses (MMTV), BALB2 and BALB14, that
encode superantigens (Sags) with Vbeta2+ and Vbeta14+ specificities, respectively, were …

Superanttgens reduce:. t% orous immune response by stimulating T cells that express
parucular T-cell receptor VI~ chains. Mouse mammary tumo; virus ts a nulk-transnutted …

Most laboratory strains of mice have between two and eight endogenous superantigens.
These viral superantigens (vSAGs) are coded by genes in the 3'long terminal repeats of …

It took nearly 100 years from the first description of mammary tumors in wild mice (Crisp,
1854) to the discovery that an extrachromosomal factor was responsible for the high …

Mouse mammary tumor virus (MMTV) encodes a superantigen that is important for viral
infectivity in vivo. To determine whether superantigen function was required for infection by …

It is clear that there is genetic variation among different individuals in their susceptibility to
infection by viruses and other pathogens. Identification of the genes involved in conferring …

Mouse mammary tumor virus (MMTV) has developed a strategy of exploitation of the
immune response. It infects dendritic cells and B cells and requires this infection to establish …

Mouse mammary tumour virus (MMTV) is a type B retrovirus that causes mammary tumours
in susceptible mice. MMTV encodes a superantigen (SAg) that has the property of …