Major haemorrhage is a leading cause of morbidity and mortality worldwide. Successful
treatment requires early recognition, planned responses, readily available resources (such …

This clinical review explored coagulopathy in severely bleeding patients after major surgery
(eg, cardiac surgery with cardiopulmonary bypass or CPB), serious trauma, and postpartum …

Importance Critical bleeding is associated with a high mortality rate in patients with trauma.
Hemorrhage is exacerbated by a complex derangement of coagulation, including an acute …

Background In-hospital acute resuscitation in trauma has evolved toward early and
balanced transfusion resuscitation with red blood cells (RBC) and plasma being transfused …

Platelet transfusions are commonly administered for the prevention or treatment of bleeding
in patients with acquired thrombocytopenia across a range of clinical contexts. Recent data …

Background Timely and accurate identification of life-and limb-threatening injuries (LLTIs) is
a fundamental objective of trauma care that directly informs triage and treatment decisions …

This document is an update of the multidisciplinary document HEMOMAS, published in 2016
with the endorsement of the Spanish Scientific Societies of Anaesthesiology (SEDAR) …

A consumptive coagulopathy describes a situation where there is a loss of hemostatic
factors, which leads to an increased risk of bleeding. Some recent studies have used the …

Postpartum hemorrhage (PPH) is usually caused by obstetrical complications but may be
exacerbated by hemostatic impairment. Standard laboratory tests of coagulation often take …

When platelet concentrates (PCs) were first introduced in the 1960s as a blood component
therapy, they were stored in the cold. As platelet transfusion became more important for the …