Pain associated with mechanical, chemical, and thermal heat stimulation of the ocular
surface is mediated by trigeminal ganglion neurons, while cold thermoreceptors detect …

Neurotrophic Keratopathy (NK) refers to a condition where corneal epitheliopathy leading to
frank epithelial defect with or without stromal ulceration (melting) is associated with reduced …

The word “elective” refers to medications and procedures undertaken by choice or with a
lower grade of prioritization. Patients usually use elective medications or undergo elective …

In the cornea, resident immune cells are in close proximity to sensory nerves, consistent with
their important roles in the maintenance of nerves in both homeostasis and inflammation …

Tissue-resident macrophages form an essential part of the first line of defense in all tissues
of the body. Next to their immunological role, they play an important role in maintaining …

Aniridia, a rare congenital disease, is often characterized by a progressive, pronounced
limbal insufficiency and ocular surface pathology termed aniridia-associated keratopathy …

The transparency of the cornea along with its dense sensory innervation and resident
leukocyte populations make it an ideal tissue to study interactions between the nervous and …

Plasmacytoid dendritic cells (pDCs) are a unique subpopulation of immune cells, distinct
from classical dendritic cells. pDCs are generated in the bone marrow and following …

Background Dry eye causes corneal inflammation, epitheliopathy and sensorineural
changes. This study evaluates the hypothesis that dry eye alters the percentages and …

The mature peripheral nervous system is a steady network structure yet shows remarkable
regenerative properties. The interaction of peripheral nerves with myeloid cells has largely …