Transforming growth factor-β (TGFβ) isoforms are upregulated and activated in myocardial
diseases and have an important role in cardiac repair and remodelling, regulating the …

Background: Molecules secreted by Trypanosoma cruzi (T. cruzi) have beneficial effects on
the immune system and can fight against cancer by inhibiting the growth of tumor cells …

Chagas disease is a neglected tropical disease caused by the parasite Trypanosoma cruzi.
Chronic Chagas cardiomyopathy (CCC), the most severe form of target organ involvement in …

Chronic manifestations of Chagas disease present as disabling and life-threatening
conditions affecting mainly the cardiovascular and gastrointestinal systems. Although …

Chagas disease (CD), a neglected tropical illness caused by the protozoan Trypanosoma
cruzi, affects more than 6 million people mostly in poor areas of Latin America. CD has two …

Background We assessed the effects of exercise-based training programs (EBTP) in patients
with chronic Chagas cardiomyopathy (CCC) through a systematic review and meta-analysis …

Introduction Chronic Chagasic cardiomyopathy (CCC), caused by the protozoan
Trypanosoma cruzi, is the most severe manifestation of Chagas disease. CCC is …

The need for new drugs to treat human infections is a global health concern. Diseases like
tuberculosis, trypanosomiasis, amoebiasis, and AIDS remain significant problems …

Statins, also known as HMG-CoA reductase inhibitors, are widely prescribed drugs for the
prevention and treatment of cardiovascular diseases. In addition to their lipid-lowering …

Chagas cardiomyopathy (CC), caused by the protozoan Trypanosoma cruzi, is an important
cause of cardiovascular morbidity and mortality in developing countries. It is estimated that 6 …